NCT07413055 Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial
| NCT ID | NCT07413055 |
| Status | Recruiting |
| Phase | Phase 3 |
| Sponsor | Oman Ministry of Health |
| Condition | Postoperative Pain |
| Study Type | INTERVENTIONAL |
| Enrollment | 138 participants |
| Start Date | 2026-03-25 |
| Primary Completion | 2026-11-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
Phase 3 trials are large pivotal studies comparing the treatment to current standard of care or placebo. Your participation directly contributes to the evidence needed for regulatory approval.
This trial targets 138 participants in total. It began in 2026-03-25 with a primary completion date of 2026-11-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to compare the effectiveness of 4mg and 8mg dexamethasone administered submucosally in reducing postoperative pain after dental implant surgery. Participants will be randomly assigned to receive either 4mg dexamethasone, 8mg dexamethasone, or a placebo (normal saline) at the surgical site. Later, postoperative pain will be assessed using a Visual Analog Scale at 6 hours after the surgery and daily for the next 6 days. Also the number of pain-relief tablets consumed after the surgery will be recorded. Preoperative anxiety will be assessed using Generalized Anxiety Disorder-7 (GAD-7) questionnaire to assess its association with postoperative pain scores. The results of this study will help determine the optimal dose of dexamethasone that is effective for postoperative pain control following dental implant surgery.
Eligibility Criteria
Inclusion Criteria: * Males \& females * Age range (21-80) * ASA I \& II according to (American Society of Anesthesiologists) classification * Single tooth implant * Type 3 \& type 4 implant placement timing (Chen and Buser, 2009) Exclusion Criteria: * Any known allergy to any medications which will be used in the study * Smokers/ Alcoholics * Pregnant and lactating women * Bone augmentation/ sinus lifting required during the surgery * The need of antibiotic prophylaxis
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07413055 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, up to 80 Years, studying Postoperative Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
What phase is the NCT07413055 trial and what does that mean for participants?
Phase 3 trials are large-scale studies comparing the new treatment to existing standards of care or a placebo. They provide the evidence needed for regulatory approval. This trial targets 138 participants.
Is NCT07413055 currently recruiting?
Yes, NCT07413055 is actively recruiting participants. Contact the research team at shurooqalhinai@gmail.com for enrollment information.
Where is the NCT07413055 trial being conducted?
This trial is being conducted at Muscat, Oman.
Who is sponsoring the NCT07413055 clinical trial?
NCT07413055 is sponsored by Oman Ministry of Health. The trial plans to enroll 138 participants.