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Recruiting NCT07268261

NCT07268261 Combined Method of Surgical Treatment of Anal Fissure

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Clinical Trial Summary
NCT ID NCT07268261
Status Recruiting
Phase
Sponsor State Scientific Centre of Coloproctology, Russian Federation
Condition Chronic Anal Fissure
Study Type INTERVENTIONAL
Enrollment 122 participants
Start Date 2023-09-01
Primary Completion 2025-12-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 70 Years
Study Type INTERVENTIONAL
Interventions
excision of the anal fissure with further relaxation of the internal sphincter with botulinum toxin A

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 122 participants in total. It began in 2023-09-01 with a primary completion date of 2025-12-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this study is to improve treatment outcomes for patients with chronic anal fissure.

Eligibility Criteria

Inclusion Criteria: * • Patients with chronic anal fissure with spasm of anal sphincter Exclusion Criteria: * • Inflammatory diseases of the colon * Pectenosis * Previous surgical interventions on the anal canal * IV grade internal and external hemorrhoids * Rectal fistula * Severe somatic diseases at the decompensation stage * Pregnancy and lactation * Anal sphincter insufficiency * Chronic paraproctitis * Individual intolerance and hypersensitivity to botulinum toxin * Myasthenia gravis and myasthenic syndromes * History of allergic reaction to anticoagulants. * Blood diseases (thrombocytopenia, splenomegaly, etc.)

Contact & Investigator

Central Contact

Evgeny E. Zharkov, MD

✉ drzharkov@mail.ru

📞 +79039689739

Principal Investigator

Sergey A. Frolov, Ph.D

PRINCIPAL INVESTIGATOR

State Scientific Centre of Coloproctology, Russian Federation (SSCCRussia)

Frequently Asked Questions

Who can join the NCT07268261 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Chronic Anal Fissure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07268261 currently recruiting?

Yes, NCT07268261 is actively recruiting participants. Contact the research team at drzharkov@mail.ru for enrollment information.

Where is the NCT07268261 trial being conducted?

This trial is being conducted at Moscow, Russia.

Who is sponsoring the NCT07268261 clinical trial?

NCT07268261 is sponsored by State Scientific Centre of Coloproctology, Russian Federation. The principal investigator is Sergey A. Frolov, Ph.D at State Scientific Centre of Coloproctology, Russian Federation (SSCCRussia). The trial plans to enroll 122 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology