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Recruiting NCT04184375

NCT04184375 Cognitive Stimulation for Elderly Bipolar Patients

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Clinical Trial Summary
NCT ID NCT04184375
Status Recruiting
Phase
Sponsor Groupe Hospitalier de la Rochelle Ré Aunis
Condition Bipolar Disorder
Study Type INTERVENTIONAL
Enrollment 40 participants
Start Date 2021-03-04
Primary Completion 2026-03-03

Eligibility & Interventions

Sex All sexes
Min Age 65 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
cognitive stimulation

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 40 participants in total. It began in 2021-03-04 with a primary completion date of 2026-03-03.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Age is a major risk factor for the development of cognitive disorders and neurodegenerative pathologies. Cognitive disorders during the phases of bipolar disease are known to exist, and alterations increase significantly after the age of 65. Drug treatments seem to have only a limited effect. A cognitive stimulation program has proven his benefit to patients over 65 with neurodegenerative diseases (Israel, 2004). We propose to evaluate this cognitive stimulation program that we have adapted to bipolar disease.

Eligibility Criteria

Pre-Inclusion Criteria: * age \> 65 years old * Diagnosis of bipolar illness for more than 10 years * Euthymic phase * Understands and speaks French * Free, informed and express consent Inclusion Criteria: * Mild to moderate neuro-cognitive impairments (MMS Test : 16 ≤ score \< 26) Exclusion Criteria: * Illiteracy * Patient participating in other therapeutic workshops (e. g. psycho-geriatric day hospital care, etc.) * Persons deprived of their liberty by a judicial or administrative decision * Persons of full age who are subject to a legal protection measure * Persons unable to consent * Persons who are not members of or beneficiaries of a social security scheme * Patient's refusal to participate in the study

Contact & Investigator

Central Contact

Caroline ALLIX-BEGUEC, Ph.D.

✉ caroline.allix-beguec@ght-atlantique17.fr

📞 +33 (0) 516 49 42 46

Principal Investigator

Pascale Puzos, MD

STUDY DIRECTOR

Groupe Hospitalier de la Rochelle Ré Aunis

Frequently Asked Questions

Who can join the NCT04184375 clinical trial?

This trial is open to participants of all sexes, aged 65 Years or older, studying Bipolar Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04184375 currently recruiting?

Yes, NCT04184375 is actively recruiting participants. Contact the research team at caroline.allix-beguec@ght-atlantique17.fr for enrollment information.

Where is the NCT04184375 trial being conducted?

This trial is being conducted at La Rochelle, France.

Who is sponsoring the NCT04184375 clinical trial?

NCT04184375 is sponsored by Groupe Hospitalier de la Rochelle Ré Aunis. The principal investigator is Pascale Puzos, MD at Groupe Hospitalier de la Rochelle Ré Aunis. The trial plans to enroll 40 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology