NCT06215274 Cognitive Leisure and Preclinical Alzheimer's Disease: Exploring Neural Mechanisms
| NCT ID | NCT06215274 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Yuanjiao Yan |
| Condition | Cognitive Dysfunction |
| Study Type | OBSERVATIONAL |
| Enrollment | 156 participants |
| Start Date | 2024-04-27 |
| Primary Completion | 2026-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 156 participants in total. It began in 2024-04-27 with a primary completion date of 2026-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is aims to: 1. Translate and culturally adapt the Cognitive Leisure Activity Scale (CLAS) into Chinese and Conduct reliability and validity tests for the Chinese version of CLAS. 2. Investigate the correlation between cognitive leisure activity levels and cognitive function in the preclinical stage of Alzheimer's Disease (AD). 3. Clarify the regulatory mechanisms of cognitive leisure activity levels on the neural circuits of patients in the preclinical stage of AD.
Eligibility Criteria
Inclusion Criteria: * Clinical diagnosis of Mild Cognitive Impairment (MCI) and Subjective Cognitive Decline (SCD) * Age ≥ 60 years * Capable of normal communication in Mandarin，possesses a certain level of comprehension and judgment. Exclusion Criteria: * Individuals with severe hearing or language impairments, or with severe physical illnesses that are unable to cooperate with the survey * Individuals with pacemakers, metallic implants, cochlear implants, claustrophobia, and other contraindications for MRI examination.
Contact & Investigator
Yuanjiao Yan, PHD
STUDY DIRECTOR
Fujian Provincial Hospital\Shengli clinical medical college of Fujian Medical university
Frequently Asked Questions
Who can join the NCT06215274 clinical trial?
This trial is open to participants of all sexes, aged 60 Years or older, studying Cognitive Dysfunction. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06215274 currently recruiting?
Yes, NCT06215274 is actively recruiting participants. Contact the research team at fjslkyk@163.com for enrollment information.
Where is the NCT06215274 trial being conducted?
This trial is being conducted at Fuzhou, China.
Who is sponsoring the NCT06215274 clinical trial?
NCT06215274 is sponsored by Yuanjiao Yan. The principal investigator is Yuanjiao Yan, PHD at Fujian Provincial Hospital\Shengli clinical medical college of Fujian Medical university. The trial plans to enroll 156 participants.