NCT06631781 Cognitive Control Mechanisms in Older Adults
| NCT ID | NCT06631781 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Hebrew University of Jerusalem |
| Condition | Depressive Symptoms |
| Study Type | INTERVENTIONAL |
| Enrollment | 42 participants |
| Start Date | 2024-02-02 |
| Primary Completion | 2024-12 |
Trial Parameters
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Brief Summary
The prevalence of depressive symptoms in older adults is on the rise, affecting 13 to 37% of older adults globally. These symptoms significantly impact health, increasing the risk of dementia and cognitive decline, and impairing daily functioning and quality of life. Reduced cognitive control (CC) is a key factor contributing to depressive symptoms, affecting 40% of adults with such symptoms. Despite this, over half of affected adults do not respond well to available treatments. Computerized cognitive training (CCT) has shown efficacy in improving CC but its impact on daily functioning is limited. The Cognitive Orientation to Occupational Performance (CO-OP) approach has demonstrated promise in improving daily functioning, as measured by occupational performance (OP). We propose a novel intervention, GOLD-Cog+, combining CCT and CO-OP, to address CC and functional deficits in older adults with depressive symptoms.
Eligibility Criteria
Inclusion Criteria: * Depressive Symptoms based on Patient Health Questionnaire (PHQ-8) ≥ 5 * Healthy Cognition based on Montreal Cognitive Assessment (MoCa) ≥ 20 * Capable of signing and agreeing to participate in the study * Have the basic technological skills to use a tablet based on self-report * Adequate sight and hearing abilities (with assistive technology) to be able to use a tablet and fully participate in a small group setting (6 people) * Ability to fluently read, speak and understand Hebrew or English Exclusion Criteria: * Any neurodegenerative disorder (e.g., Mild Cognitive Impairment (MCI), Dementia, Parkinson's disease) via self-report * Psychiatric disorders, not including depression or anxiety disorders (specifically: Schizophrenia, Bipolar or Psychotic disorders) via self-report