NCT02579278 Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion
| NCT ID | NCT02579278 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Imperial College London |
| Condition | Cancer |
| Study Type | OBSERVATIONAL |
| Enrollment | 100 participants |
| Start Date | 2015-11 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 100 participants in total. It began in 2015-11 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study does not involve randomization or treatment. Eligible patients have colorectal adenocarcinoma with no metastases eligible for curative surgery. A pre operative staging scan must have been completed within 6 weeks prior to surgery. Two x 20ml blood samples will be taken from each patient, one prior to and one during or within 24hrs after surgery. Patients are annually followed up to 3 years.
Eligibility Criteria
Inclusion Criteria: 1. Have a biopsy-confirmed colorectal adenocarcinoma 2. Is eligible for curative surgery 3. Has no metastatic disease on CT scan 4. Has completed pre-operative staging scan within six weeks prior to surgery 5. Have provided written informed consent to participate in the study 6. Be aged 16 years or over Exclusion Criteria: 1. Have metastatic disease (including resectable liver metastases) 2. Have a synchronous second malignancy 3. Are contraindicated for any imaging able to determine EMVI status
Contact & Investigator
Gina Brown, MD
PRINCIPAL INVESTIGATOR
Imperial College London
Frequently Asked Questions
Who can join the NCT02579278 clinical trial?
This trial is open to participants of all sexes, aged 16 Years or older, studying Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT02579278 currently recruiting?
Yes, NCT02579278 is actively recruiting participants. Contact the research team at c.martin1@imperial.ac.uk for enrollment information.
Where is the NCT02579278 trial being conducted?
This trial is being conducted at Margate, United Kingdom, Hammersmith, United Kingdom, Sutton, United Kingdom.
Who is sponsoring the NCT02579278 clinical trial?
NCT02579278 is sponsored by Imperial College London. The principal investigator is Gina Brown, MD at Imperial College London. The trial plans to enroll 100 participants.
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