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Recruiting NCT04175691

NCT04175691 Circulating Non-coding RNA in Acute Ischemic Stroke (AISRNA)

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Clinical Trial Summary
NCT ID NCT04175691
Status Recruiting
Phase
Sponsor Nanjing First Hospital, Nanjing Medical University
Condition Acute Stroke
Study Type OBSERVATIONAL
Enrollment 500 participants
Start Date 2019-11-24
Primary Completion 2026-12-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Sequencing of circRNA/miRNA/lncRNA

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 500 participants in total. It began in 2019-11-24 with a primary completion date of 2026-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

AISRNA is to analyze the expression pattern of circular RNA (circRNA), micro-RNA (miRNA) and long non-coding RNA (lncRNA) by next-generation sequencing in patients with acute ischemic stroke and healthy control. The candidate circRNA/miRNA/lncRNA will be verified as biomarkers for the detection and prognosis of acute ischemic stroke.

Eligibility Criteria

Inclusion Criteria: * Aged 18 years or older * Confirmed acute ischemic stroke by a diffusion-weighted imaging-position lesion on magnetic resonance imaging (MRI) and a new lesion on a brain computed tomography (CT) scan * Within 72 hours of symptom onset * Good performance status * Signed an approved informed consents Exclusion Criteria: -a history of hemorrhagic infarction, chronic kidney/liver diseases, peripheral arterial occlusive disease, active malignant disease, and inflammatory or infectious diseases

Contact & Investigator

Central Contact

Junshan Zhou, M.D.

✉ zhjsh333@126.com

📞 +8602587726218

Principal Investigator

Junshan Zhou, Professor

STUDY CHAIR

Nanjing Medical University

Frequently Asked Questions

Who can join the NCT04175691 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Acute Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04175691 currently recruiting?

Yes, NCT04175691 is actively recruiting participants. Contact the research team at zhjsh333@126.com for enrollment information.

Where is the NCT04175691 trial being conducted?

This trial is being conducted at Nanjing, China.

Who is sponsoring the NCT04175691 clinical trial?

NCT04175691 is sponsored by Nanjing First Hospital, Nanjing Medical University. The principal investigator is Junshan Zhou, Professor at Nanjing Medical University. The trial plans to enroll 500 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology