NCT07665216 Chatbot Intervention Effects on Resting-State Brain Function in Anhedonia
| NCT ID | NCT07665216 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Electronic Science and Technology of China |
| Condition | Healthy |
| Study Type | INTERVENTIONAL |
| Enrollment | 80 participants |
| Start Date | 2026-06-20 |
| Primary Completion | 2028-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 80 participants in total. It began in 2026-06-20 with a primary completion date of 2028-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The main aim of the present study is to investigate the effects of a Motivational Interviewing-based artificial intelligence chatbot on resting-state brain function in college students with elevated anhedonia and depressive symptoms. The study will use a randomized active-control intervention design with pre- and post-intervention resting-state functional magnetic resonance imaging assessments.
Eligibility Criteria
Inclusion Criteria: * 18-40 years * Right-handed * Normal or corrected normal visual acuity * Participants must show elevated anhedonia and depressive symptoms at screening, defined as a total score of 23.5 or higher on the Snaith-Hamilton Pleasure Scale and a score of 14 or higher on the Beck Depression Inventory Exclusion Criteria: * History of major central nervous system disorders, such as epilepsy, traumatic brain injury, stroke, or brain tumors. * History of severe mental illness, including schizophrenia spectrum disorders, bipolar disorder, or other psychotic disorders. * History of substance or alcohol use disorder or substance or alcohol misuse within the past 12 months that may affect study participation or outcome assessment. * Individuals currently at high risk of suicide, severe self-harm, or experiencing an acute psychiatric crisis. * Individuals who are currently using psychiatric medications or have undergone psychotherapy within the past 4 weeks that may significantly affect mood, motivation, or reward processing. * Severe vision or hearing impairments that cannot be corrected and would interfere with task performance. * Contraindications to MRI scanning, including metallic implants, pacemakers, severe claustrophobia, or other conditions incompatible with MRI. * Pregnancy or breastfeeding.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07665216 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 40 Years, studying Healthy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07665216 currently recruiting?
Yes, NCT07665216 is actively recruiting participants. Contact the research team at bbecker@hku.hk for enrollment information.
Where is the NCT07665216 trial being conducted?
This trial is being conducted at Chengdu, China.
Who is sponsoring the NCT07665216 clinical trial?
NCT07665216 is sponsored by University of Electronic Science and Technology of China. The trial plans to enroll 80 participants.