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Recruiting NCT07466602

NCT07466602 cfDNA Methylation for Liver Cancer Recurrence Detection

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Clinical Trial Summary
NCT ID NCT07466602
Status Recruiting
Phase
Sponsor Wuhan Ammunition Life-tech Co., Ltd
Condition Primary Liver Cancer
Study Type OBSERVATIONAL
Enrollment 500 participants
Start Date 2025-09-02
Primary Completion 2027-06-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
plasma GNB4 and Riplet genes methylation detection

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 500 participants in total. It began in 2025-09-02 with a primary completion date of 2027-06-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Through follow-up testing of patients with primary liver cancer who underwent hepatectomy, liver transplantation, ablation therapy, or transarterial chemoembolization (TACE), a blinded comparative trial was conducted at each monitoring site. This trial evaluated the combined methylation detection kit for GNB4 and Riplet genes (fluorescent PCR method) against the clinical reference standard (defined as the physician's comprehensive diagnosis based on clinical guidelines and other criteria). The study evaluated the clinical performance of the assay in diagnosing primary liver cancer recurrence and validated the clinical efficacy of methylation detection kits for monitoring recurrence after primary liver cancer treatment.

Eligibility Criteria

Inclusion Criteria: * Primary liver cancer Exclusion Criteria: * Concurrent other malignant tumors; * Ineligible for hepatectomy, liver transplantation, ablation, or TACE therapy; * Negative methylation status prior to treatment.

Contact & Investigator

Central Contact

Tingting Li, phD

✉ litingting@amswh.com

📞 +86 13317163570

Frequently Asked Questions

Who can join the NCT07466602 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Primary Liver Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07466602 currently recruiting?

Yes, NCT07466602 is actively recruiting participants. Contact the research team at litingting@amswh.com for enrollment information.

Where is the NCT07466602 trial being conducted?

This trial is being conducted at Wuhan, China.

Who is sponsoring the NCT07466602 clinical trial?

NCT07466602 is sponsored by Wuhan Ammunition Life-tech Co., Ltd. The trial plans to enroll 500 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology