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Recruiting NCT06773065

Central Awareness in Women With Endometriosis

Trial Parameters

Condition Endometriosis
Sponsor IRCCS Azienda Ospedaliero-Universitaria di Bologna
Study Type OBSERVATIONAL
Phase N/A
Enrollment 310
Sex FEMALE
Min Age 18 Years
Max Age 50 Years
Start Date 2022-01-14
Completion 2025-01-31

Brief Summary

Gathering some information obtained during the gynaecological examination and transvaginal ultrasound check-up to be able to assess the prevalence of Central Sensitisation Syndrome (CSS) in women with endometriosis and also to be able to assess related risk factors. CSS has been defined as an algic syndrome due to a hyperactivation of the sensitivity circuit at a central level; the diagnosis is based on the result obtained from a questionnaire, the Central Sensitisation Inventory (CSI), which evaluates the presence and intensity of 25 clinical symptoms. For this reason, a questionnaire is proposed to be completed at the time of the check-up visit.

Eligibility Criteria

Inclusion Criteria: * Women with a clinical, ultrasound and/or surgical diagnosis of endometriosis * Aged between 18 and 50 years * Patients starting or already taking hormone therapy * Patients coming for a first visit or outpatient follow-up visit * Signature of informed consent to participate in the study Exclusion Criteria: * Post-menopausal women (spontaneous or iatrogenic) * Virgo patients * Patients with poor compliance with hormone therapy, who are not taking it properly or have discontinued therapy spontaneously * Positive history of any malignant neoplasm * Positive medical history of specific medical conditions that adversely affect the central nervous system, such as: brain or spinal cord damage, neurological diseases or peripheral nerve damage, multiple sclerosis

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