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Recruiting Phase 3 NCT06120400

Cardiovascular Effects of a Healthy Dietary Pattern Containing Eggs

Trial Parameters

Condition Cardiovascular Diseases
Sponsor Penn State University
Study Type INTERVENTIONAL
Phase Phase 3
Enrollment 65
Sex ALL
Min Age 30 Years
Max Age 60 Years
Start Date 2024-04-25
Completion 2026-07
Interventions
Whole Egg

Brief Summary

This study will examine the effect of a healthy diet containing 2 eggs per day compared to a healthy diet containing 3 eggs per week on biomarkers of heart health after 4 weeks.

Eligibility Criteria

Inclusion Criteria: * LDL-C ≥115 mg/dL and ≤190 mg/L * BMI of 25-35 kg/m2 * Intake of \<14 eggs/week for the prior 3 months * Blood pressure \<140/90 mmHg * Fasting blood glucose \<126 mg/dL * Fasting triglycerides \<350 mg/dL * ≤10% change in body weight in the prior 6 months Exclusion Criteria: * Type 1 or type 2 diabetes or fasting blood glucose ≥126 mg/dL * Prescription of anti-hypertensive, lipid lowering or glucose lowering drugs * Intake of supplements that affect the outcomes of interest and unwilling to cease during the study period * Diagnosed liver, kidney, or autoimmune disease * Prior cardiovascular event (e.g., stroke, heart attack) * Current pregnancy or intention of pregnancy within the next 6 months * Lactation within prior 6 months * Follows a vegetarian or vegan diet * Food allergies/intolerance/sensitives/dislikes of foods included in the study menu * Antibiotic use within the prior 1 month * Oral steroid use within the prior 1 month * Use of tobacco or nicotine con

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