NCT07529145 Cardiopulmonary Exercise Testing in Lung Cancer Patients Before and During Oncological Treatment
| NCT ID | NCT07529145 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Medical University of Bialystok |
| Condition | Non-Small Cell Carcinoma of Lung |
| Study Type | OBSERVATIONAL |
| Enrollment | 90 participants |
| Start Date | 2026-01-01 |
| Primary Completion | 2027-03-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 90 participants in total. It began in 2026-01-01 with a primary completion date of 2027-03-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Patients with lung cancer often have reduced physical fitness and coexisting health problems, which may limit their ability to tolerate oncological treatment. Standard resting lung and heart tests do not always reflect real-life physical capacity during everyday activities or physical effort. This observational study aims to assess cardiorespiratory fitness in patients with lung cancer before and during standard oncological treatment using cardiopulmonary exercise testing (CPET). CPET is a safe, supervised exercise test that provides objective information on how the heart, lungs, and muscles respond to physical effort. Participants with WHO/ECOG performance status 0-2 will undergo CPET before treatment initiation and again after the early phase of therapy or surgery. The results may help identify patients with reduced physiological reserve and support individualized monitoring during routine clinical care.
Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years * Histologically confirmed lung cancer (any stage) * Qualified for standard oncological management (surgery and/or systemic therapy) * WHO/ECOG performance status 0-2 * Ability to perform cardiopulmonary exercise testing (CPET) * Written informed consent Exclusion Criteria: * Unstable ischemic heart disease * Symptomatic cardiac arrhythmias * Myocarditis or pericarditis * Decompensated heart failure * Active deep vein thrombosis * Suspected aortic dissection or severe aortic stenosis * Poorly controlled asthma * Resting oxygen saturation ≤ 85% on room air * Clinically relevant treatment-related adverse events above mild intensity (as applicable) * Any medical condition that, in the investigator's opinion, precludes safe participation in CPET * Withdrawal of informed consent
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07529145 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Non-Small Cell Carcinoma of Lung. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07529145 currently recruiting?
Yes, NCT07529145 is actively recruiting participants. Contact the research team at klaudia.jadczak@sd.umb.edu.pl for enrollment information.
Where is the NCT07529145 trial being conducted?
This trial is being conducted at Bialystok, Poland.
Who is sponsoring the NCT07529145 clinical trial?
NCT07529145 is sponsored by Medical University of Bialystok. The trial plans to enroll 90 participants.