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Recruiting NCT06702059

NCT06702059 Cardiopulmonary Exercise Testing in Cardiosurgery Patients

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Clinical Trial Summary
NCT ID NCT06702059
Status Recruiting
Phase
Sponsor St. Anne's University Hospital Brno, Czech Republic
Condition Postoperative Complications
Study Type OBSERVATIONAL
Enrollment 130 participants
Start Date 2024-12-01
Primary Completion 2027-12-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Cardiopulmonary exercise testing

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 130 participants in total. It began in 2024-12-01 with a primary completion date of 2027-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Cardiopulmonary exercise testing (CPET) is considered to be a gold standard in pre-operative risk assessment and stratification of high risk patients scheduled for major surgery. Surprisingly, only a limited number of studies examined the prognostic role of CPET in cardiothoracic surgery. This is in contrast with rather poor discriminating quality of cardiovascular surgery risk scores and predominantly elderly cardiovascular surgery patients, with significant comorbidity and high degree of frailty. Recently, CPET was shown feasible in coronary artery bypass grafting surgery candidates. Additionally, the rest parameter, which is the partial pressure of end-tidal carbon dioxide (PETCO2) and a submaximal exercise parameter (the VE/VCO2 slope) with good prognostic utility across multiple respiratory exchange ratio values), has been shown to predict mortality and post-operative complications. Whether these rest and submaximal exercise parameters can be used to predict postoperative complications in cardiovascular surgery patients is yet to be determined.

Eligibility Criteria

Inclusion Criteria: * patients scheduled for coronary artery bypass graft surgery Exclusion Criteria: * not able to perform cardiopulmonary exercise testing, off-pump revascularization, without full sternotomy, previous cardiac surgery

Contact & Investigator

Central Contact

Ivan Cundrle, prof., M.D.

✉ Ivan.Cundrle@fnusa.cz

📞 00420 543182553

Principal Investigator

Ivan Cundrle, prof., M.D.

PRINCIPAL INVESTIGATOR

St. Anne's University Hospital

Frequently Asked Questions

Who can join the NCT06702059 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Postoperative Complications. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06702059 currently recruiting?

Yes, NCT06702059 is actively recruiting participants. Contact the research team at Ivan.Cundrle@fnusa.cz for enrollment information.

Where is the NCT06702059 trial being conducted?

This trial is being conducted at Brno, Czechia, Brno, Czechia.

Who is sponsoring the NCT06702059 clinical trial?

NCT06702059 is sponsored by St. Anne's University Hospital Brno, Czech Republic. The principal investigator is Ivan Cundrle, prof., M.D. at St. Anne's University Hospital. The trial plans to enroll 130 participants.

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