NCT04713774 Bone Density and Vascular Calcifications Evolution After Renal Transplant
| NCT ID | NCT04713774 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Liege |
| Condition | Kidney Transplant; Complications |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2020-09-01 |
| Primary Completion | 2025-12-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 50 participants in total. It began in 2020-09-01 with a primary completion date of 2025-12-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The investigators project is based on: * Assessment of bone architecture by high resolution peripheral scanner (HRpQCT) and bone densitometry (DEXA); * The non-invasive detection of vascular calcifications (by abdominal CT scanner) and bone abnormalities associated with kidney transplantation, as well as the analysis of evolution over time; * Longitudinal evaluation of nephrological clinical parameters (glomerular filtration rate, number and type of rejections, immunosuppressive medications) as well as biological and urinary parameters of mineral metabolism (parathormone, sclerostin, bone alkaline phosphatase) depending on the type and severity of bone abnormalities; * The evaluation of these nephrological clinical parameters and of the biological parameters of mineral metabolism depending on the extent and evolution of vascular calcifications but also on bone morphology; * The study of possible relationships between bone mass and muscle mass (and functioning)
Eligibility Criteria
Inclusion Criteria: * At least 18 years old * Recent kidney transplant patients (\<3 months) * Medical history available * Biological parameters of the past year available Exclusion Criteria: * Treatment with bisphosphonate, RANKL inhibitor or SERM with bone action in the last 3 months before the transplant * Multiple organ transplant patients
Contact & Investigator
Antoine Bouquegneau
PRINCIPAL INVESTIGATOR
University of Liege
Frequently Asked Questions
Who can join the NCT04713774 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Kidney Transplant; Complications. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04713774 currently recruiting?
Yes, NCT04713774 is actively recruiting participants. Contact the research team at antoine.bouquegneau@gmail.com for enrollment information.
Where is the NCT04713774 trial being conducted?
This trial is being conducted at Liège, Belgium.
Who is sponsoring the NCT04713774 clinical trial?
NCT04713774 is sponsored by University of Liege. The principal investigator is Antoine Bouquegneau at University of Liege. The trial plans to enroll 50 participants.
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