NCT06527742 Body Composition, Frailty, and Function in Rehabilitation
| NCT ID | NCT06527742 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Changi General Hospital |
| Condition | Frailty |
| Study Type | OBSERVATIONAL |
| Enrollment | 345 participants |
| Start Date | 2024-12-09 |
| Primary Completion | 2025-09 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 345 participants in total. It began in 2024-12-09 with a primary completion date of 2025-09.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The investigators are investigating if body composition measures - in particular muscle mass, body fat, and something called the phase angle - are able to reliably predict functional outcomes for patients who are in an acute hospital for inpatient rehabilitation. The investigators also want to see if age and frailty affect these relationships. Patients undergoing inpatient rehabilitation in our hospital will be monitored through a variety of frailty-specific tools, including strength and speed. The investigators will use a device called a body composition monitor (BCM) to record their body composition measurements. These will then be compared against their usual rehabilitation outcomes. The investigators believe that there is a correlation between these measures and a patient's functional outcomes.
Eligibility Criteria
Inclusion Criteria: 1. Transferred under the Rehabilitation Medicine service for post-acute rehabilitation 2. Rehabilitation diagnosis of: 1. Stroke with motor weakness (modified Rankin scale 1-5), or 2. Deconditioning (from sepsis, post-ICU admission, heart failure, falls, musculoskeletal conditions with or without pain, or other conditions), or 3. Pulmonary rehabilitation (with or with long-term oxygen therapy), or 4. Lower limb amputees (transtibial or transfemoral) 3. Medically stable 4. Able to understand English consent form or suitably-translated document, or have a family member/legally-authorised representative who is able to do so and willing to provide consent Exclusion Criteria: 1. Pacemaker or implantable defibrillator in-situ 2. Medical devices or surgical implants that will interfere with BIA measurement per the manufacturer's guidelines 3. Abnormal fluid status (overloaded or depleted) at the point of screening 4. Cognitive or physical inability to tolerate sitting/lying still for 2mins (for BIA measurement)
Contact & Investigator
Edmund JR Neo, MBBS
PRINCIPAL INVESTIGATOR
Singapore Health Services Pte Ltd
Frequently Asked Questions
Who can join the NCT06527742 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, studying Frailty. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06527742 currently recruiting?
Yes, NCT06527742 is actively recruiting participants. Contact the research team at edmund.neo.jin.rui@singhealth.com.sg for enrollment information.
Where is the NCT06527742 trial being conducted?
This trial is being conducted at Singapore, Singapore.
Who is sponsoring the NCT06527742 clinical trial?
NCT06527742 is sponsored by Changi General Hospital. The principal investigator is Edmund JR Neo, MBBS at Singapore Health Services Pte Ltd. The trial plans to enroll 345 participants.