NCT06314009 Beyond MARS: Magnetic Resonance Study: A Novel Assessment of Placental Perfusion During Pregnancy
| NCT ID | NCT06314009 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Endeavor Health |
| Condition | Pregnancy |
| Study Type | OBSERVATIONAL |
| Enrollment | 30 participants |
| Start Date | 2024-05-09 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 30 participants in total. It began in 2024-05-09 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to evaluate the flow of oxygen and blood necessary for nutrient transfer across the placenta during the second and third trimesters in pregnancy in women who are obese before pregnancy compared to women who have an average weight before pregnancy. This study will evaluate blood flow across the placenta by functional Magnetic Resonance Imaging (fMRI). The investigators hypothesize that there will be differences in placental oxygenation and blood flow among women with obesity as compared to those with normal weight. Participants will be asked to complete: * MRI in the second trimester (20-24 weeks) * MRI in the third trimester (30-34 weeks)
Eligibility Criteria
Inclusion Criteria: * Singleton pregnancy, less than 24 weeks gestation * Pre-pregnancy BMI between 18.5 - 24.9kg/m2 or ≥30kg/m2 Exclusion Criteria: * Asthma on controller medication * Autoimmune Conditions * Chronic Hypertension * Claustrophobia * Congenital Anomaly * Pregestational Diabetes * History of Bariatric Surgery * HIV * Ineligible for MRI (incompatible implanted medical device) * Multifetal Gestation * Smoking during pregnancy
Contact & Investigator
Caitlin MacGregor
PRINCIPAL INVESTIGATOR
Endeavor Health
Frequently Asked Questions
Who can join the NCT06314009 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 60 Years, studying Pregnancy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06314009 currently recruiting?
Yes, NCT06314009 is actively recruiting participants. Contact the research team at alexandra.mangus@endeavorhealth.org for enrollment information.
Where is the NCT06314009 trial being conducted?
This trial is being conducted at Evanston, United States.
Who is sponsoring the NCT06314009 clinical trial?
NCT06314009 is sponsored by Endeavor Health. The principal investigator is Caitlin MacGregor at Endeavor Health. The trial plans to enroll 30 participants.