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Recruiting Phase 1, Phase 2 NCT06237179

Behavioral Exercise Training to Reduce Cardiovascular Disease Risk

Trial Parameters

Condition Prostate Cancer
Sponsor Virginia Commonwealth University
Study Type INTERVENTIONAL
Phase Phase 1, Phase 2
Enrollment 60
Sex MALE
Min Age 40 Years
Max Age 85 Years
Start Date 2024-02-21
Completion 2028-01-31
Interventions
Exercise Training InterventionHealthy Living Education

Brief Summary

To test the preliminary effectiveness of a home-based exercise training (ET) intervention to improve exercise capacity (VO2 peak \& 6-minute walk distance \[6MWD\]) among prostate cancer (PC) patients compared to controls receiving healthy living education (HLE) at 12 weeks.

Eligibility Criteria

Inclusion Criteria: * Be diagnosed with stage II/III/IV prostate cancer * Be currently undergoing treatment with ADT (intermittent or prolonged) * Have completed local curative-intent treatment, including prostatectomy or definitive radiation; * Be \>40 years of age up to 85; * Be willing to sign an informed consent with HIPAA authorization form; * Not have any hearing or sight impairments that result in the inability to use the telephone or hear normal conversation; * Must be able to join an intervention group by personal computer, smartphone or telephone call and should agree to recording of an interview; * Be without any serious medical condition that precludes safe participation in an exercise program; * Speak English Exclusion Criteria: * Be unable to undergo MRI (i.e., ferromagnetic materials in body, inability to lie flat, claustrophobia); * Have contraindications to exercise testing; * Have pre-existing overt cardiovascular disease/heart failure; * Active illness/infection; * H

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