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Recruiting Phase 2 NCT07317206

NCT07317206 Ayahuasca, Esketamine and PTSD

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Clinical Trial Summary
NCT ID NCT07317206
Status Recruiting
Phase Phase 2
Sponsor University of Sao Paulo
Condition Posttraumatic Stress Disorder (PTSD)
Study Type INTERVENTIONAL
Enrollment 10 participants
Start Date 2025-12-20
Primary Completion 2026-06

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 65 Years
Study Type INTERVENTIONAL
Interventions
AyahuascaEsketamine

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.

This trial targets 10 participants in total. It began in 2025-12-20 with a primary completion date of 2026-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Double-blind, randomized trial comparing a single dose of oral ayahuasca or esketamine in patients with posttraumatic stress disorder.

Eligibility Criteria

Inclusion Criteria: * posttraumatic stress disorder Exclusion Criteria: * psychiatric and other medical comorbidities

Frequently Asked Questions

Who can join the NCT07317206 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Posttraumatic Stress Disorder (PTSD). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT07317206 trial and what does that mean for participants?

Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.

Is NCT07317206 currently recruiting?

Yes, NCT07317206 is actively recruiting participants. Visit ClinicalTrials.gov or contact University of Sao Paulo to inquire about joining.

Where is the NCT07317206 trial being conducted?

This trial is being conducted at Ribeirão Preto, Brazil.

Who is sponsoring the NCT07317206 clinical trial?

NCT07317206 is sponsored by University of Sao Paulo. The trial plans to enroll 10 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology