NCT07610876 Autologous Demineralized Dentin Graft With or Without Melatonin for Immediate Implant Osseointegration
| NCT ID | NCT07610876 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Suez Canal University |
| Condition | Dental Implants |
| Study Type | INTERVENTIONAL |
| Enrollment | 16 participants |
| Start Date | 2025-08-11 |
| Primary Completion | 2026-10-10 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 16 participants in total. It began in 2025-08-11 with a primary completion date of 2026-10-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized clinical study aims to evaluate the effect of autologous demineralized dentin graft (ADDG) with or without melatonin gel on the osseointegration of immediately placed dental implants in the maxillary premolar region. Sixteen patients requiring extraction and immediate implant placement will be randomly allocated into two groups. Clinical and radiographic outcomes including implant stability, peri-implant probing depth, modified bleeding index, marginal bone loss, buccal bone thickness, and bone density will be evaluated over a 9-month follow-up period.
Eligibility Criteria
Inclusion Criteria: * Age above 20 years * Non-restorable maxillary premolar teeth * Candidates for immediate implant placement * Intact socket walls * Jumping gap \>2 mm * Non-smokers or light smokers * No acute infection * Adequate bone for primary stability Exclusion Criteria: * Heavy smokers * Bruxism or clenching * Uncontrolled systemic disease * Chemotherapy/radiotherapy * Immunocompromised patients
Contact & Investigator
Hany Kamel Shalaby
STUDY CHAIR
Professor of Oral Medicine and Periodontology, Dean Faculty of Dentistry
Frequently Asked Questions
Who can join the NCT07610876 clinical trial?
This trial is open to participants of all sexes, aged 20 Years or older, studying Dental Implants. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07610876 currently recruiting?
Yes, NCT07610876 is actively recruiting participants. Contact the research team at PGS.230043@dent.suez.edu.eg for enrollment information.
Where is the NCT07610876 trial being conducted?
This trial is being conducted at Ismailia, Egypt.
Who is sponsoring the NCT07610876 clinical trial?
NCT07610876 is sponsored by Suez Canal University. The principal investigator is Hany Kamel Shalaby at Professor of Oral Medicine and Periodontology, Dean Faculty of Dentistry. The trial plans to enroll 16 participants.