NCT06602141 Assessments of Adipogenesis, Lipid Turnover and Cellular Composition in Adipose Tissue in Response to Endurance Exercise
| NCT ID | NCT06602141 |
| Status | Recruiting |
| Phase | — |
| Sponsor | AdventHealth Translational Research Institute |
| Condition | Obesity |
| Study Type | INTERVENTIONAL |
| Enrollment | 70 participants |
| Start Date | 2024-09-11 |
| Primary Completion | 2029-04 |
Trial Parameters
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Brief Summary
The purpose of this research study is to study the effects of endurance exercise training on adipose (fat) tissue quality and insulin sensitivity in men and women.
Eligibility Criteria
Inclusion Criteria: 1. Men and pre-menopausal women; 2. 18-45 years of age; 3. BMI 30.0-40.0 kg/m2; 4. For women, if not using pharmaceutical (hormonal) contraception (i.e. birth control pills, vaginal ring, injections, or implant), must agree to use either a double barrier method as a form of birth control to prevent pregnancy (i.e. male condom with spermicide, with or without cervical cap or diaphragm); use implants or intrauterine contraceptive devices; have a tubal ligation (surgically sterile); practice abstinence; or be in an established relationship with a vasectomized or same sex partner during the entire duration of the study; 5. Able to speak and understand written and spoken English; 6. Sedentary defined as self-reporting no more than 1 day per week, lasting no more than 60 minutes, of regular (structured) endurance or resistance exercise in the past year. 7. Must be willing to be randomized to either study group; 8. Must be willing to adhere to all study procedures. 9. Part
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