NCT07178288 Assessment of Pressure Pain Threshold (PPT) and Conditioned Pain Modulation (CPM) After Effect in Patients With and Without Tennis Elbow (TE)
| NCT ID | NCT07178288 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The Hashemite University |
| Condition | Tennis Elbow |
| Study Type | INTERVENTIONAL |
| Enrollment | 38 participants |
| Start Date | 2025-09-10 |
| Primary Completion | 2025-12-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 38 participants in total. It began in 2025-09-10 with a primary completion date of 2025-12-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study at Hashemite University looks at how people with and without tennis elbow (AKA lateral elbow tendinopathy) feel pressure pain and how their bodies briefly "turn down" pain after a cold stimulus. Participants complete brief questionnaires (basic demographics without names, a tennis-elbow symptom form, and a physical-activity form) and then have their pressure-pain threshold (PPT) tested with a handheld device that slowly increases pressure on standard spots near the elbow and wrist; they say when it first becomes painful. To test the body's built-in anti-pain system (conditioned pain modulation, CPM), one hand is placed in ice water (the cold-pressor task) and PPT is measured again at set times (before, during, and after the cold stimulus) to see how much pain sensitivity changes and how long that change lasts. Both PPT reliability and CPM after effect are measured in this study. The study findings may help improve future assessment and treatment of musculoskeletal pain conditions.
Eligibility Criteria
TE Group Inclusion Criteria: Patients with Tennis Elbow confirmed at initial assessment by the Primary Investigator (PI) Unilateral elbow pain \> 6 weeks duration reproduced on at least two of the following tests: * Palpation of the lateral epicondyle * Isometric testing of the wrist extensors * Middle finger extension test * Passive stretch of wrist extensors * Resisted hand gripping using a dynamometer * Upper limb neurodynamic test-radial nerve bias (ULNDT-RN) Exclusion Criteria: * History of chronic pain conditions (e.g. fibromyalgia, irritable bowel * syndrome, temporomandibular dysfunction, migraines) * Neurological or sensory dysfunction (especially in the upper limbs) * History of chronic musculoskeletal pain (e.g. arthritis, chronic low back * pain) * Contraindications to cold application (i.e. Reynaud's disease, diabetes) * Current or long-term use of pain medication or anti-depressants Healthy Group The asymptomatic group included adults (18-65 years) without pain (acute or chronic) at least 3 months before the experimental sessions.
Contact & Investigator
Ahmad Muhsen
PRINCIPAL INVESTIGATOR
The Hashemite University
Frequently Asked Questions
Who can join the NCT07178288 clinical trial?
This trial is open to participants of all sexes, up to 60 Years, studying Tennis Elbow. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07178288 currently recruiting?
Yes, NCT07178288 is actively recruiting participants. Contact the research team at muhsen_a@hu.edu.jo for enrollment information.
Where is the NCT07178288 trial being conducted?
This trial is being conducted at Zarqa, Jordan.
Who is sponsoring the NCT07178288 clinical trial?
NCT07178288 is sponsored by The Hashemite University. The principal investigator is Ahmad Muhsen at The Hashemite University. The trial plans to enroll 38 participants.