NCT05108896 Aspiration in Acute Respiratory Failure Survivors 2
| NCT ID | NCT05108896 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Colorado, Denver |
| Condition | Dysphagia |
| Study Type | INTERVENTIONAL |
| Enrollment | 855 participants |
| Start Date | 2021-12-15 |
| Primary Completion | 2025-12-15 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 855 participants in total. It began in 2021-12-15 with a primary completion date of 2025-12-15.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to learn more about problems with swallowing that could develop in patients who are very sick and need a machine to help them breathe.
Eligibility Criteria
Inclusion Criteria: 1. Admission to an ICU. 2. Mechanical ventilation with an endotracheal tube for greater than 48 hours. Exclusion Criteria: 1. Likely persistent contraindications to enteral/oral nutrition administration. 2. Pre-existing history of dysphagia or aspiration. 3. Pre-existing or acute primary central or peripheral neuromuscular disorder. 4. Presence of a chronic tracheostomy (present prior to ICU admission). 5. Pre-existing head and neck cancer or surgery. 6. Coagulopathy resulting in uncontrolled nasal or pharyngeal bleeding. 7. Delirium for more than 96 hours after extubation as assessed by Confusion Assessment Method (CAM-ICU). 8. Extubated for greater than 96 hours. 9. Inability to obtain informed consent from patient or an appropriate surrogate. 10. Age \< 18 years.
Contact & Investigator
Marc Moss, MD
PRINCIPAL INVESTIGATOR
University of Colorado, Denver
Frequently Asked Questions
Who can join the NCT05108896 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Dysphagia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05108896 currently recruiting?
Yes, NCT05108896 is actively recruiting participants. Contact the research team at jeffrey.mckeehan@cuanschutz.edu for enrollment information.
Where is the NCT05108896 trial being conducted?
This trial is being conducted at Stanford, United States, Aurora, United States, New Haven, United States, Boston, United States and 1 additional location.
Who is sponsoring the NCT05108896 clinical trial?
NCT05108896 is sponsored by University of Colorado, Denver. The principal investigator is Marc Moss, MD at University of Colorado, Denver. The trial plans to enroll 855 participants.