NCT06672315 Application of Transesophageal Echocardiography in Pre-hospital Cardiac Arrest Patients
| NCT ID | NCT06672315 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Jen-Tang Sun |
| Condition | Out-of-hospital Cardiac Arrest (OHCA) |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2024-12-30 |
| Primary Completion | 2027-08-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2024-12-30 with a primary completion date of 2027-08-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The Use of Point-of-Care Ultrasound (POCUS), Transthoracic Echocardiography (TTE), and Transesophageal Echocardiography (TEE) in Cardiac Arrest and Acute Coronary Syndrome Patients Studies have shown that POCUS can rapidly change the management in nearly 80% of cases in emergency settings, particularly in environments such as war zones and disaster relief. TTE is highly sensitive in diagnosing acute coronary syndromes and can effectively rule out myocardial infarction. In cardiac arrest patients, TTE assists in determining cardiac activity and identifying reversible causes, such as pericardial tamponade and pneumothorax. However, TTE can be affected by suboptimal image quality due to factors like chest compression in out-of-hospital cardiac arrest (OHCA) patients. In Taiwan's emergency medical system, EMT-Ps (paramedics) undergo approximately one year of training, which enables them to provide emergency care, including ultrasound examinations, before hospital arrival. Research on pre-hospital cardiac arrest has shown that most ultrasound applications can be completed within 3 minutes and do not significantly increase on-scene time. TEE, though advantageous for its high-quality imaging and ability to reduce interruptions during chest compressions, faces challenges in pre-hospital emergency applications due to specialized training and equipment requirements. However, a study in Vienna, Austria, demonstrated that TEE could be performed and yield high-quality images in most pre-hospital cases, with an average examination time of 5.1 minutes. Several hospitals in Taiwan have begun training personnel in TEE, emphasizing the importance of establishing TEE image registries for large-scale, effective research analysis. However, these efforts also face challenges related to resources and collaboration. The research team has over three years of experience using TEE in the emergency department to examine OHCA patients, and a three-year study will be conducted to validate the efficacy of pre-hospital TEE in cardiac arrest patients.
Eligibility Criteria
Inclusion Criteria: 1. Age ≥ 18 years 2. Patients with out-of-hospital cardiac arrest (OHCA) 3. Non-traumatic cause of cardiac arrest Exclusion Criteria: 1. Presence of obvious signs of death, such as decapitation, rigor mortis, livor mortis, or decomposition. 2. Family explicitly expresses a Do Not Attempt Resuscitation (DNR) order, or the patient has a documented refusal of resuscitation. 3. Any condition that contraindicates the use of transesophageal echocardiography (TEE), such as esophageal tumors, preventing probe insertion. 4. Patients eligible for ECPR (Extracorporeal Cardiopulmonary Resuscitation) treatment. 5. Spontaneous circulation has already been stabilized before performing TEE.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06672315 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Out-of-hospital Cardiac Arrest (OHCA). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06672315 currently recruiting?
Yes, NCT06672315 is actively recruiting participants. Contact the research team at femhresearch@gmail.com for enrollment information.
Where is the NCT06672315 trial being conducted?
This trial is being conducted at New Taipei City, Taiwan.
Who is sponsoring the NCT06672315 clinical trial?
NCT06672315 is sponsored by Jen-Tang Sun. The trial plans to enroll 60 participants.