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Recruiting NCT03981653

ANgiogenic Function at NOrmal TErm on Placenta

Trial Parameters

Condition Pregnancy Related
Sponsor Centre Hospitalier Intercommunal Creteil
Study Type OBSERVATIONAL
Phase N/A
Enrollment 750
Sex FEMALE
Min Age 18 Years
Max Age N/A
Start Date 2019-03-20
Completion 2029-03

Brief Summary

In vivo and ex vivo study of trophoblastic angiogenic trophoblastic function in placentas from normal pregnancies, at term

Eligibility Criteria

Inclusion Criteria: * Pregnancies with scheduled cesarean delivery \>37 weeks of amenorrhea: * strictly normal pregnancies * complicated pregnancies of gestational diabetes, insulin-treated or not * complicated pregnancies due to pregnancy cholestasis * spontaneous or in vitro fecondation (IVF) / Intracytoplasmic sperm injection (ICSI) pregnancies with or without oocyte donation Exclusion Criteria: * Patient's opposition * Age \< 18 years old * Women under the protection of justice * Multiple pregnancy * Known major fetal malformation * Pre-eclampsia and intrauterine growth retardation * Placental insertionnomaly * Type 1 diabetes * HIV-positive patient with HIV/hepatisis C virus (HCV) regardless of viral load * Patient in labour at the time of Caesarean section * Patient whose medical history results in medication being taken in pregnancy courses that may interfere with the biology of the trophoblast (immunomodulators in case of autoimmune diseases, anti-rejection drugs in case of tra

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