NCT06535230 Anesthesia Induction with the Target-controlled Infusion of Propofol in High-risk Patients
| NCT ID | NCT06535230 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Acibadem University |
| Condition | Anesthesia |
| Study Type | INTERVENTIONAL |
| Enrollment | 200 participants |
| Start Date | 2024-08-30 |
| Primary Completion | 2025-05-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 200 participants in total. It began in 2024-08-30 with a primary completion date of 2025-05-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to compare the risk of hypotension following induction of anesthesia in high-risk patients (American Society of Anesthesiologists risk scores III and IV) using target-controlled infusion (TCI) of propofol versus standard manual induction of anesthesia. Our previously published study compared TCI and manual induction of anesthesia in a general patient population and found that hypotension developed less with TCI induction. This study is a continuation of the other study and will be conducted in high-risk patients.
Eligibility Criteria
Inclusion Criteria: * Patients with the American Society of Anesthesiology physical status 3-4 * Underwent major elective surgery * Required intra-arterial blood pressure monitoring before induction. Exclusion Criteria: * Under 18 years of age * Patients with the American Society of Anesthesiology physical status 1-2 * Arrhythmia (atrial fibrillation, frequent premature beat) * Severe valvular heart disease * Morbid obesity * Intubation difficulty * Drug addiction * Treatment with opiates * Pregnancy * Emergency surgery
Contact & Investigator
Fevzi Toraman, M.D.
STUDY DIRECTOR
Acibadem Mehmet Ali Aydinlar University School of Medicine, Department of Anesthesiology
Frequently Asked Questions
Who can join the NCT06535230 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 100 Years, studying Anesthesia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06535230 currently recruiting?
Yes, NCT06535230 is actively recruiting participants. Contact the research team at serapaktas79@yahoo.com.tr for enrollment information.
Where is the NCT06535230 trial being conducted?
This trial is being conducted at Istanbul, Turkey (Türkiye).
Who is sponsoring the NCT06535230 clinical trial?
NCT06535230 is sponsored by Acibadem University. The principal investigator is Fevzi Toraman, M.D. at Acibadem Mehmet Ali Aydinlar University School of Medicine, Department of Anesthesiology. The trial plans to enroll 200 participants.