NCT06408012 An Innovative Master Platform for Clinical Trials in Mood Disorders
| NCT ID | NCT06408012 |
| Status | Recruiting |
| Phase | — |
| Sponsor | St. Joseph's Healthcare Hamilton |
| Condition | Mood Disorders |
| Study Type | OBSERVATIONAL |
| Enrollment | 900 participants |
| Start Date | 2023-10-17 |
| Primary Completion | 2026-03-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 900 participants in total. It began in 2023-10-17 with a primary completion date of 2026-03-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Mood disorders such as depression and bipolar disorder affect over 350 million people around the world. While several effective treatments exist, it is often difficult to match the right treatment to an individual person. Repeated efforts to find the right treatment contribute to poor functioning, low quality of life, and prolongs the time it takes to get well. Most areas of medicine are able to use 'biomarkers' or clinical tests, blood tests, or imaging to help diagnose and treat illness. The search for biomarkers in mood disorders is advancing, but one roadblock to progress is the lack of large, standardized studies of mood disorders that are needed to accurately identify biomarkers. The aim of the ENABLE platform is to provide the Canadian neuroscience community a standardized way of collecting biomarker data from individuals with a range of mood disorders symptoms. In addition, this 'master clinical trial platform' framework will provide a pool of participants who can be recruited into biomarker-based clinical trials.
Eligibility Criteria
Inclusion Criteria Patients: 1. 16 years of age or older. 2. Meet criteria for bipolar or depressive disorders as defined by DSM-5. 3. Fluency in English, sufficient to complete the interviews and self-report questionnaires. Inclusion Criteria Healthy Comparison (HC) Participants: 1. 16 years of age or older. 2. No history of psychiatric disorders (according to DSM-5) or significant unstable medical conditions. 3. Fluency in English, sufficient to complete the interviews and self-report questionnaires.
Contact & Investigator
Benicio N Frey
PRINCIPAL INVESTIGATOR
St. Joseph's Healthcare Hamilton
Frequently Asked Questions
Who can join the NCT06408012 clinical trial?
This trial is open to participants of all sexes, aged 16 Years or older, studying Mood Disorders. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06408012 currently recruiting?
Yes, NCT06408012 is actively recruiting participants. Contact the research team at skhoshro@stjoes.ca for enrollment information.
Where is the NCT06408012 trial being conducted?
This trial is being conducted at Calgary, Canada, Vancouver, Canada, Halifax, Canada, Hamilton, Canada and 5 additional locations.
Who is sponsoring the NCT06408012 clinical trial?
NCT06408012 is sponsored by St. Joseph's Healthcare Hamilton. The principal investigator is Benicio N Frey at St. Joseph's Healthcare Hamilton. The trial plans to enroll 900 participants.