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Recruiting NCT07675694

NCT07675694 AI Timing in Chest X-ray Interpretation Using Eye-Tracking

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Clinical Trial Summary
NCT ID NCT07675694
Status Recruiting
Phase
Sponsor University Hospitals, Leicester
Condition Diagnostic Imaging
Study Type INTERVENTIONAL
Enrollment 24 participants
Start Date 2026-06-30
Primary Completion 2026-12

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Original CXR First TimingAI Output First Timing

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 24 participants in total. It began in 2026-06-30 with a primary completion date of 2026-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Chest X-rays are commonly used to help diagnose and manage chest conditions. Artificial intelligence (AI) tools are increasingly being used to support chest X-ray interpretation. However, it is not yet clear whether the timing of AI information affects how clinicians review images, make decisions, and use AI support. This study will look at whether showing AI information before or after a clinician first reviews a chest X-ray changes how they look at the image, how long they take, their interpretation decisions, their confidence, and their trust in AI support. Healthcare professional participants will complete two chest X-ray interpretation sessions in a controlled NHS research setting. During each session, participants will review de-identified chest X-ray images while wearing eye-tracking equipment. Eye-tracking will record where a participant looks on the image and how long they spend looking at different areas. In one session, AI information will be shown before the participant reviews the chest X-ray. In the other session, AI information will be shown after the participant has first reviewed the chest X-ray. The order of these two sessions will be balanced across participants. The study uses de-identified chest X-ray images from existing examinations. It does not involve patients directly, does not change clinical care, and no clinical decisions will be made from the study readings. Participants will also complete a short questionnaire about their experience of using AI support. A separate anonymous survey will collect wider views from clinicians, patients, members of the public, and healthcare staff about the use of AI in chest X-ray interpretation.

Eligibility Criteria

Inclusion Criteria: Main reader study: * Healthcare professionals aged 18 years or over * Registered to practise in the UK * Employed by the NHS or another healthcare service operating in the UK * Current or recent, within the last 3 years, clinical experience involving chest X-ray interpretation, review, or use in clinical practice * Able to attend two onsite study sessions at University Hospitals of Leicester NHS Trust at mutually agreed times * Able and willing to provide written informed consent * Compatible with the eye-tracking equipment Supplementary survey: * Adults aged 18 years or over * Live in the UK or have used the NHS or another UK healthcare service within the last 5 years * Able to provide informed electronic consent * Belong to one of the following respondent groups: healthcare professionals or healthcare staff, patients or carers, or members of the public * Healthcare professional respondents may include adults involved in requesting, interpreting, checking, or acting on chest X-ray findings in clinical practice Exclusion Criteria: Main reader study: * Inability to attend both onsite study sessions at University Hospitals of Leicester NHS Trust * Eye-tracking incompatibility, such as visual, neurological, or physical conditions preventing adequate gaze tracking or participant comfort * Direct involvement in selection, adjudication, or preparation of the chest X-rays used in the study * Conflicts of interest, including direct involvement in development of the AI system under evaluation * Prior participation in a closely related AI chest X-ray study where overlap in image sets or study procedures may compromise validity, assessed on a case-by-case basis Supplementary survey: * Aged under 18 years * Does not live in the UK and has not used the NHS or another UK healthcare service within the last 5 years * Unable to provide informed electronic consent * Does not meet one of the eligible respondent groups for the survey

Contact & Investigator

Central Contact

Richard Farley

✉ richard.farley1@nhs.net

📞 +44116258 6237

Frequently Asked Questions

Who can join the NCT07675694 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Diagnostic Imaging. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07675694 currently recruiting?

Yes, NCT07675694 is actively recruiting participants. Contact the research team at richard.farley1@nhs.net for enrollment information.

Where is the NCT07675694 trial being conducted?

This trial is being conducted at Leicester, United Kingdom.

Who is sponsoring the NCT07675694 clinical trial?

NCT07675694 is sponsored by University Hospitals, Leicester. The trial plans to enroll 24 participants.

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