NCT06765551 AI Based Muscular Ultrasound to Assess Intensive Care Unit-acquired Weakness
| NCT ID | NCT06765551 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Jena University Hospital |
| Condition | Intensive Care Unit-acquired Weakness |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2024-10-01 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 50 participants in total. It began in 2024-10-01 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aim of this observational case-control study is to investigate, whether artificial intelligence can detect ultrasound-derived imaging characteristics typical for intensive care unit-acquired weakness. The main questions it aims to answer are: 1. Is the evaluation of specific parameters of neuromuscular ultrasound using AI-based image analysis suitable for detecting and monitoring critically ill ICU patients with ICUAW? 2. Do the results of AI-based ultrasound image analysis correlate with: (A) the severity of ICUAW (B) the visual grading of muscle echogenicity (C) the 30- and 90-day-outcome?
Eligibility Criteria
Inclusion Criteria: * Patients aged 18 years or above * Major elective surgery, e.g. cardiothoracic or abdominal surgery * Expected ICU stay \>1 day postoperatively * Healthy, age-machted subjects without ICUAW (recruited from staff of the department of anesthesiology and intensive care medicine) Exclusion Criteria: * No informed consent * Emergency surgery * Previous participation in the same study * Preexisting neuromuscular disease * Preexisting central nervous system disease with residual neuromuscular impairment (e.g. cerebral haemorrhage, stroke, brain tumor) * High-dose glucocorticoid therapy (\>300 mg hydrocortisone or equivalent per day) before or during particiation in the study
Contact & Investigator
PD Dr. Johannes Ehler, M.D.
PRINCIPAL INVESTIGATOR
Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital
Frequently Asked Questions
Who can join the NCT06765551 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Intensive Care Unit-acquired Weakness. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06765551 currently recruiting?
Yes, NCT06765551 is actively recruiting participants. Contact the research team at johannes.ehler@med.uni-jena.de for enrollment information.
Where is the NCT06765551 trial being conducted?
This trial is being conducted at Jena, Germany.
Who is sponsoring the NCT06765551 clinical trial?
NCT06765551 is sponsored by Jena University Hospital. The principal investigator is PD Dr. Johannes Ehler, M.D. at Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital. The trial plans to enroll 50 participants.