NCT07614542 AGEWISE: Unravelling the Gut-Hormone Axis in Women's Ageing
| NCT ID | NCT07614542 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Gulbenkian Institute for Molecular Medicine |
| Condition | Menopause |
| Study Type | OBSERVATIONAL |
| Enrollment | 300 participants |
| Start Date | 2025-06-02 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 300 participants in total. It began in 2025-06-02 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
AGEWISE is an observational study that aims to understand how changes in gut microbiome are related to hormonal changes during women's ageing, particularly across the different stages of menopause. The study will include healthy women aged 40 to 64 years living in Portugal, who will provide stool and blood samples and complete questionnaires about their health, lifestyle, diet, and menopausal symptoms. Researchers will study the gut microbiome together with hormone levels and markers of inflammation to better understand how menopause affects long-term health and to support the development of improved prevention strategies for women.
Eligibility Criteria
Inclusion Criteria: * Female sex * Aged 40 to 64 years * Resident in mainland Portugal or the islands * Able and willing to provide written informed consent * Willing to provide stool and blood samples and complete three questionnaires Exclusion Criteria: * Age below 40 years or 65 years and older * Inability to give informed consent * Refusal to provide stool or blood samples or complete questionnaires * Pregnancy * Diagnosed gastrointestinal disorders (including inflammatory bowel disease, Crohn's disease, ulcerative colitis, irritable bowel syndrome, chronic diarrhoea of unknown cause, or recurrent Clostridioides difficile infection) * Active oncological disease
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07614542 clinical trial?
This trial is open to female participants only, aged 40 Years or older, up to 64 Years, studying Menopause. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07614542 currently recruiting?
Yes, NCT07614542 is actively recruiting participants. Contact the research team at ana.almeida@gimm.pt for enrollment information.
Where is the NCT07614542 trial being conducted?
This trial is being conducted at Lisbon, Portugal.
Who is sponsoring the NCT07614542 clinical trial?
NCT07614542 is sponsored by Gulbenkian Institute for Molecular Medicine. The trial plans to enroll 300 participants.