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Recruiting NCT06539104

Aftificial Inteligence in Assisted Reproductive Techniques to Assess Oocyte Quality and Embryo Ploidy

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Plain-language summary for patients

Trial Parameters

Condition Infertility
Sponsor Charles University, Czech Republic
Study Type OBSERVATIONAL
Phase N/A
Enrollment 1,000
Sex ALL
Min Age 18 Years
Max Age 49 Years
Start Date 2024-01-05
Completion 2027-12-31
Interventions
arteficial inteligence evaluation of oocyte and embryo development

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Brief Summary

The assisted reproduction success rate is affected by several factors including the age of the women, oocyte quality and maturation state, as well as sperm quality. Imaging of the meiotic spindle may be crucial for determining the oocyte maturation. Artificial intelligence (AI) will be applied to establish the complex oocyte quality, embryo ploidy and pregnancy success probability from the sequence of data, starting with the recording of the meiotic spindle in polarized light, through paternal factors up to the time lapse recording of early embryo development. This strategy should reduce the cost of fertility treatment thanks to increased efficiency in choosing the most promising candidates and reducing the need for costly laboratory analyses.

Eligibility Criteria

Inclusion Criteria: * Intracytoplasmatic Sperm Injection * Preimplantation genetic testing * Time lapse embryo record * Singned informed consent Exclusion Criteria: * Gynecological diseases * Genetical diseases of parents

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