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Recruiting NCT06523270

NCT06523270 Advanced Imaging Holistic Omics Biobank

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Clinical Trial Summary
NCT ID NCT06523270
Status Recruiting
Phase
Sponsor IRCCS San Raffaele
Condition Oncologic Disorders
Study Type OBSERVATIONAL
Enrollment 50,000 participants
Start Date 2024-09-15
Primary Completion 2034-09-15

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Computed Tomography (CT) using Photon Counting CT scanner (Neaotom Alpha, Siemens) and Magnetic Resonance (MRI)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 50,000 participants in total. It began in 2024-09-15 with a primary completion date of 2034-09-15.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Imaging methods today represent the pillar of prevention, diagnosis, patients monitoring and treatment. Improvement in technology led the development of increasingly high-performance scanners whose potential has not yet been fully explored. In particular, recently introduced photon counting CT scanner and new high filed MRI offers a lake of latent information derived from the images (e.g. spectral data from CT) of potentially great interest and potentially able to provide new insight but that are currently mostly unexplored .These features are also called "opportunist features" because they are in each exam and can be freely derived from images without changing the study protocol used for clinical practice examination but extracted a posteriori from the images representing a precious source of deep characterization of the patients, equally or even more than a genomic analysis, with possible high relevance in the field of screening and prevention, being able to contribute to defining signatures indicating a particular risk of remotely developing a specific pathological condition. The prospective collection of clinical and imaging data from subjects undergoing diagnostic tests with advanced technology has the potential to increase knowledge of the pathophysiological mechanisms of different pathological conditions, to explore and validate the diagnostic-predictive value of opportunistic features not currently used in practice clinical, to increase the diagnostic and prognostic accuracy of CT and MRI examinations and to provide a unique pool for scientific research. Previous relevant experience was conducted in the United Kingdom (UK biobank) where data from over 500,000 patients have been collected in the last 10 years, providing an enormous pool for spontaneous and funded scientific research. This project (UK biobank), although of enormous scientific value, is currently obsolete in terms of the imaging technology used.

Eligibility Criteria

Inclusion Criteria: * Adult subjects (\>18 y.o.) submitted to Computed Tomography (CT) using Photon Counting CT scanner (Neaotom Alpha, Siemens) and Magnetic Resonance (MRI) exams acquired with 3T scanner (MR 7700, Philips) for examination required for clinical practice or for clinical trials at the IRCCS San Raffaele Hospital who signe an Informed Consent authorizing data collection. Exclusion Criteria: * Absent informed consent signed

Contact & Investigator

Central Contact

Antonio Esposito

✉ esposito.antonio@hsr.it

📞 0226436102

Frequently Asked Questions

Who can join the NCT06523270 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Oncologic Disorders. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06523270 currently recruiting?

Yes, NCT06523270 is actively recruiting participants. Contact the research team at esposito.antonio@hsr.it for enrollment information.

Where is the NCT06523270 trial being conducted?

This trial is being conducted at Milan, Italy.

Who is sponsoring the NCT06523270 clinical trial?

NCT06523270 is sponsored by IRCCS San Raffaele. The trial plans to enroll 50,000 participants.

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