NCT07421427 Adding Amantadine or Duloxetine to Pregabalin on Occurrence of Post Mastectomy Pain Syndrome
| NCT ID | NCT07421427 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Cairo University |
| Condition | Amantadine |
| Study Type | INTERVENTIONAL |
| Enrollment | 150 participants |
| Start Date | 2026-02-21 |
| Primary Completion | 2027-01-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 150 participants in total. It began in 2026-02-21 with a primary completion date of 2027-01-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to evaluate the additive effect of Amantadine or Duloxetine to Pregabalin on development of post mastectomy pain syndrome
Eligibility Criteria
Inclusion Criteria: * Age from 18 to 65 years. * American society of anesthesiologists (ASA) Physical status II, III. * Body mass index (BMI): (20-40) kg/m2. * Type of surgery: patients undergoing modified radical mastectomy for breast cancer. Exclusion Criteria: * Patient refusal. * Patients with Known sensitivity or contraindication to drug used in the study. * History of psychological disorders and/or chronic pain and drug abuse patients. * Previous administration of antidepressants, anticonvulsants, or opioids before surgery. * Severe respiratory or cardiac disorders. * Advanced liver or kidney disease. * Previous breast surgery
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07421427 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 65 Years, studying Amantadine. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07421427 currently recruiting?
Yes, NCT07421427 is actively recruiting participants. Contact the research team at hussamhassan90@gmail.com for enrollment information.
Where is the NCT07421427 trial being conducted?
This trial is being conducted at Cairo, Egypt.
Who is sponsoring the NCT07421427 clinical trial?
NCT07421427 is sponsored by Cairo University. The trial plans to enroll 150 participants.