| NCT ID | NCT07425769 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Kansas Medical Center |
| Condition | Down Syndrome (DS) |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2026-03-31 |
| Primary Completion | 2026-07-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 40 participants in total. It began in 2026-03-31 with a primary completion date of 2026-07-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to observe feasibility and initial efficacy of a remotely delivered exercise and dementia caregiving intervention in older adults with Down syndrome and their caregivers.
Eligibility Criteria
Inclusion Criteria - Adults with Down syndrome: * Age \>35 yrs. with a diagnosis of DS as self-reported or reported by caregiver. This age range was selected as cognitive decline related to AD is observed at age \~31 in adults with DS. * Sufficient functional ability to understand directions, communicate preferences, wants, and needs through spoken language. * Living at home or in a supported living environment with a parent/caregiver who agrees to serve as a study partner. * Self-reported ability to participate in physical activity. Exclusion Criteria - Adults with Down syndrome: * Unable to participate in moderate-to-vigorous physical activity. * Self-reported, cardiovascular, metabolic or renal disease and/or signs or symptoms. Inclusion Criteria - Caregivers * Age ≥18 yrs. * Reports being a primary caregiver of an adult with DS. * English speaking. * Self-reported ability to participate in physical activity. Exclusion Criteria - Caregivers * Unable to participate in moderate PA, i.e., brisk walking. * Self-reported, cardiovascular, metabolic or renal disease and/or signs or symptoms.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07425769 clinical trial?
This trial is open to participants of all sexes, studying Down Syndrome (DS). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07425769 currently recruiting?
Yes, NCT07425769 is actively recruiting participants. Contact the research team at abodde@kumc.edu for enrollment information.
Where is the NCT07425769 trial being conducted?
This trial is being conducted at Kansas City, United States.
Who is sponsoring the NCT07425769 clinical trial?
NCT07425769 is sponsored by University of Kansas Medical Center. The trial plans to enroll 40 participants.