NCT07365254 Accurate Assessment and Intervention Research on Newborn Whole Genome Sequencing and Genetic Disease Risk
| NCT ID | NCT07365254 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Women's Hospital School Of Medicine Zhejiang University |
| Condition | Genetic Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 1,000,000 participants |
| Start Date | 2025-02-14 |
| Primary Completion | 2030-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 1,000,000 participants in total. It began in 2025-02-14 with a primary completion date of 2030-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Maternal and infant health is the foundation of public health, and its status directly reflects the overall health level of the population. With rapid socioeconomic development and increasingly severe environmental issues, health problems among women and children have become more widespread and diverse. In the new era, maternal and child health faces new challenges, with higher demands in areas such as reproductive health promotion, birth defect prevention, maternal and infant safety, and childhood disease prevention. Cohort studies, as an epidemiological research method for exploring disease etiology, involve recruiting participants before or during pregnancy and conducting follow-ups on pregnancy, childbirth, and maternal and child health outcomes after birth to identify various factors influencing diseases and health. Focusing on the early stages of life, this approach is an effective method for studying the associations between environmental, genetic, and behavioral risk factors during early life and embryonic development, fetal health, and infant health. This project plans to conduct long-term follow-ups on couples and their offspring on a family basis, while collecting biological samples at multiple time points. A systematic multi-dimensional assessment, based on clinical information and multi-omics data from the enrolled population, will be used to infer the causes of reproductive and pregnancy-related diseases and developmental abnormalities, identify new biomarkers for pregnancy-related diseases, establish predictive models, and recognize risk factors in the early life of offspring, thereby providing guidance for the prevention and control of reproductive and developmental diseases.
Eligibility Criteria
Inclusion Criteria: * Families with ongoing pregnancies (via assisted reproductive therap or natural conception) and newborn infants. Exclusion Criteria: * None
Contact & Investigator
Hefeng Huang
STUDY CHAIR
Women's Hospital School Of Medicine Zhejiang University
Frequently Asked Questions
Who can join the NCT07365254 clinical trial?
This trial is open to participants of all sexes, studying Genetic Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07365254 currently recruiting?
Yes, NCT07365254 is actively recruiting participants. Contact the research team at ruanhengchao@zju.edu.cn for enrollment information.
Where is the NCT07365254 trial being conducted?
This trial is being conducted at Hangzhou, China.
Who is sponsoring the NCT07365254 clinical trial?
NCT07365254 is sponsored by Women's Hospital School Of Medicine Zhejiang University. The principal investigator is Hefeng Huang at Women's Hospital School Of Medicine Zhejiang University. The trial plans to enroll 1,000,000 participants.