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Recruiting NCT05101382

NCT05101382 A Retrospective Protocol Empowering Precision Research in Colorectal Cancer (ALFAOMEGA-RETRÒ)

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Clinical Trial Summary
NCT ID NCT05101382
Status Recruiting
Phase
Sponsor IFOM ETS - The AIRC Institute of Molecular Oncology
Condition Colorectal Cancer
Study Type OBSERVATIONAL
Enrollment 500 participants
Start Date 2020-10-28
Primary Completion 2026-06

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Observation

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 500 participants in total. It began in 2020-10-28 with a primary completion date of 2026-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

ALFAOMEGA-RETRÒ will be exploited to retrospectively collect clinical and imaging data and archival samples to be used for validation and correlative studies on markers discovered by cutting-edge translational projects within the AIRC5x1000 program "Insights into the evolving heterogeneity of colorectal cancer (CRC): from mechanism to therapies" (an ongoing multi-institutional research program).

Eligibility Criteria

Inclusion Criteria: * Histologically-confirmed diagnosis of colorectal cancer (any stage). * Age \>18 years at the time of diagnosis. * Availability of clinically-annotated radio-imaging data and/or diagnostic Formalin-Fixed Paraffin Embedded (FFPE) blocks (surgical resections and/or tumor biopsies), or at least 10 slides (preferably 20). FFPE tissue blocks are always preferred to slides. * Verification that the patient could not be reached for informed consent in accordance with applicable national regulations. Exclusion Criteria: * if inclusion criteria are not met

Contact & Investigator

Central Contact

Luca Lazzari, PhD

✉ clinical.trials@ifom.eu

📞 +3902574303799

Principal Investigator

Silvia Marsoni, MD

STUDY DIRECTOR

IFOM ETS - The AIRC Institute of Molecular Oncology

Frequently Asked Questions

Who can join the NCT05101382 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Colorectal Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05101382 currently recruiting?

Yes, NCT05101382 is actively recruiting participants. Contact the research team at clinical.trials@ifom.eu for enrollment information.

Where is the NCT05101382 trial being conducted?

This trial is being conducted at Genova, Italy, Milan, Italy, Milan, Italy, Milan, Italy and 9 additional locations.

Who is sponsoring the NCT05101382 clinical trial?

NCT05101382 is sponsored by IFOM ETS - The AIRC Institute of Molecular Oncology. The principal investigator is Silvia Marsoni, MD at IFOM ETS - The AIRC Institute of Molecular Oncology. The trial plans to enroll 500 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology