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Recruiting NCT06313255
A Retrospective Observational Study on the Effects of Probiotics on HBsAg Clearance
Trial Parameters
Condition Chronic Hepatitis B
Sponsor Qilu Hospital of Shandong University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 40
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-05-09
Completion 2025-12-31
Interventions
PegIFNα2bPegIFNα2b+probioticsNucleoside analog
Brief Summary
The goal of this retrospective observational study is to find out the effects of probiotics on HBV clearance. The main question it aims to answer is: Are the probiotics have an effect in promoting HBV clearance? The participants will observe the HBV clearance rate in chronic hepatitis B patients receive probiotics in addition to the routine antiviral therapy. Researchers will compare the HBV clearance rate in chronic hepatitis B patients receive probiotics and antiviral therapy with those receiving solely antiviral therapy.
Eligibility Criteria
Inclusion Criteria: * chronic hepatitis B patients Exclusion Criteria: * patients with malignancies * patients with other liver diseases * pregnancy patients
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