NCT04981821 A Randomized Trial of a Mobile Health Exercise Intervention for Older Adults With Myeloid Neoplasms
| NCT ID | NCT04981821 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Rochester |
| Condition | Cancer |
| Study Type | INTERVENTIONAL |
| Enrollment | 170 participants |
| Start Date | 2022-01-03 |
| Primary Completion | 2027-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 170 participants in total. It began in 2022-01-03 with a primary completion date of 2027-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This is a phase 2 randomized controlled trial (RCT) to assess the preliminary efficacy of the a mobile health exercise intervention (GO-EXCAP) versus a chemotherapy education control in 100 older patients with MN receiving outpatient chemotherapy on physical function and patient-reported outcomes (fatigue, mood, and quality of life). We will also explore the effect of the intervention on TNFα and related cytokine gene promoter methylation and their gene and protein expression.
Eligibility Criteria
Inclusion Criteria: * Age ≥60 years (conventional definition of older age in clinical trials of MN) * Have a diagnosis of MN * Planned for or receiving outpatient cancer-directed treatments (participants receiving consolidative or maintenance outpatient therapies after induction chemotherapy are allowed to enroll) * English speaking * Eastern Cooperative Oncology Group (ECOG) performance status of 0-3 * No medical contraindications for exercise per oncologist * Able to walk 4 meters as part of Short Physical Performance Battery measured walk (with or without assistive device) * Able to provide informed consent Exclusion Criteria: * Physical, psychological, or social impairments that would interfere with subject's ability to participate in the study or participate in the intervention, as determined by the PI or the treating team
Contact & Investigator
Kah Poh Loh
PRINCIPAL INVESTIGATOR
University of Rochester
Frequently Asked Questions
Who can join the NCT04981821 clinical trial?
This trial is open to participants of all sexes, aged 60 Years or older, studying Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04981821 currently recruiting?
Yes, NCT04981821 is actively recruiting participants. Contact the research team at kahpoh_loh@urmc.rochester.edu for enrollment information.
Where is the NCT04981821 trial being conducted?
This trial is being conducted at Rochester, United States.
Who is sponsoring the NCT04981821 clinical trial?
NCT04981821 is sponsored by University of Rochester. The principal investigator is Kah Poh Loh at University of Rochester. The trial plans to enroll 170 participants.
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