NCT04767074 A Non-pharmacological Cough Control Therapy
| NCT ID | NCT04767074 |
| Status | Recruiting |
| Phase | — |
| Sponsor | West Park Healthcare Centre |
| Condition | Cough |
| Study Type | INTERVENTIONAL |
| Enrollment | 24 participants |
| Start Date | 2020-09-01 |
| Primary Completion | 2025-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 24 participants in total. It began in 2020-09-01 with a primary completion date of 2025-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Coughing affects almost all individuals with ILD leading to physical, psychological and social distress and prevents individuals from performing their activities of daily living, working or socialising in public places. Unfortunately, there are no licensed medications available to treat chronic cough and the few drugs that have been tried resulted in little efficacy and significant side effects. Drug-free cough control interventions have shown promise in reducing the severity and impact of coughing on patients' lives but have not been tested in individuals with ILD. This study aims to explore the feasibility and effectiveness of a non-pharmacological cough control therapy, as an adjuvant of pulmonary rehabilitation, in patients with ILD and chronic cough (\>8 weeks in duration).
Eligibility Criteria
Inclusion Criteria: * Individuals will be included if having confirmed diagnosis of any ILD by a physician (as per Canadian Thoracic Society's guideline for evaluating patients with fibrotic interstitial lung disease) and a chronic cough lasting more than 8 weeks in duration Exclusion Criteria: * self-reports of moderate or large sputum production * effective or suspected exacerbation of the respiratory condition in the past month * upper respiratory tract infection in the past month * use of angiotensin-converting enzyme inhibitor medication * changes in the prescribed medication in the previous month * evidence of traction bronchiectasis in the HRCT * evidence of other medical conditions that prevent performance of an exercise training program * unable to read or speak in English / unable to provide informed consent.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT04767074 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 85 Years, studying Cough. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04767074 currently recruiting?
Yes, NCT04767074 is actively recruiting participants. Contact the research team at ana.oliveira@westpark.org for enrollment information.
Where is the NCT04767074 trial being conducted?
This trial is being conducted at Hamilton, Canada, Toronto, Canada.
Who is sponsoring the NCT04767074 clinical trial?
NCT04767074 is sponsored by West Park Healthcare Centre. The trial plans to enroll 24 participants.