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Recruiting NCT06661174

A Cohort Study on the Efficacy of Bariatric Surgery for Rapidly Progressing Diabetic Nephropathy

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Trial Parameters

Condition Bariatric Surgeries
Sponsor China-Japan Friendship Hospital
Study Type OBSERVATIONAL
Phase N/A
Enrollment 100
Sex ALL
Min Age 18 Years
Max Age 65 Years
Start Date 2023-10-01
Completion 2025-10-30
Interventions
Bariatric surgeryNon-surgical therapy

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Brief Summary

Establish a cohort of diabetic kidney disease(DKD) patients with intensive weight loss treatment to evaluate the impact of intensive weight loss treatment on the renal prognosis of DKD and construct a prediction model for the improvement of renal outcomes after weight loss.

Eligibility Criteria

Inclusion Criteria: * Age 18 to 65 years old; * BMI\>25Kg/m2 or abdominal obesity (i.e. waist circumference\>90cm for men and\>85cm for women); * eGFR\<30ml/min/1.73m2 or urinary microalbumin≥300mg/g, eGFR\<60ml/min/1.73m2. Exclusion Criteria: * Patients who are taking glucocorticoids; * Combined with tumors; ③Combined with autoimmune diseases; ④Serum albumin\<25g/L.

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