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endometrial cancer Clinical Trials in United States

Active clinical trials for endometrial cancer with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.

Active Trials: 22 // Recruiting: 22 Phases: Phase 2, Phase 1 // Updated: Daily
Total Trials
22
Recruiting Now
22
Country
🇺🇸 United States

Active Trials in United States (22)

NCT06906341 Phase 2
Recruiting

Relacorilant in Combination With Different Treatment Regimens in Patients With Gynecological Cancers

Enrollment
270 pts
Country
🇺🇸 United States
Corcept Therapeutics
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NCT05103683 Phase 1
Recruiting

First in Human Study of TORL-1-23 in Participants With Advanced Cancer

Enrollment
90 pts
Country
🇺🇸 United States
TORL Biotherapeutics, LLC
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NCT05856981 Phase 1
Recruiting

Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors

Enrollment
130 pts
Country
🇺🇸 United States
Sairopa B.V.
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NCT04291612
Recruiting

Observational Study of Women With Endometrial Cancer Who Receive the Standard Treatment for Their Disease

Enrollment
1,715 pts
Country
🇺🇸 United States
Memorial Sloan Kettering Cancer Cen...
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NCT04104776 Phase 1, Phase 2
Recruiting

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

Enrollment
300 pts
Country
🇺🇸 United States
Novartis Pharmaceuticals
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NCT07270666
Recruiting

ctDNA Testing to Inform Standard-of-Care Treatment Decisions in People With Endometrial Cancer

Enrollment
30 pts
Country
🇺🇸 United States
Memorial Sloan Kettering Cancer Cen...
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NCT05983432 Phase 1
Recruiting

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

Enrollment
470 pts
Country
🇺🇸 United States
SystImmune Inc.
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NCT06242470 Phase 1
Recruiting

A Study of MGC026 in Participants With Advanced Solid Tumors

Enrollment
250 pts
Country
🇺🇸 United States
MacroGenics
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NCT07544680
Recruiting

Endometrial Cancer Vaginal Fluid Specimen Collection Study

Enrollment
4,200 pts
Country
🇺🇸 United States
Exact Sciences Corporation
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NCT07419841 Phase 1
Recruiting

A Phase 1 Study of the Safety and Tolerability of CTX-10726

Enrollment
70 pts
Country
🇺🇸 United States
Compass Therapeutics
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NCT04196257 Phase 1
Recruiting

BP1001-A in Patients With Advanced or Recurrent Solid Tumors

Enrollment
50 pts
Country
🇺🇸 United States
Bio-Path Holdings, Inc.
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NCT05377996 Phase 1, Phase 2
Recruiting

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

Enrollment
360 pts
Country
🇺🇸 United States
Day One Biopharmaceuticals, Inc.
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NCT07278986 EARLY_Phase 1
Recruiting

CYTALUX for Intraoperative Imaging of Patients With Endometrial Cancer

Enrollment
10 pts
Country
🇺🇸 United States
Abramson Cancer Center at Penn Medi...
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NCT06989112 Phase 3
Recruiting

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Enrollment
600 pts
Country
🇺🇸 United States
AstraZeneca
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NCT06840886 Phase 1
Recruiting

A Study of PHST001 in Advanced Solid Tumors

Enrollment
272 pts
Country
🇺🇸 United States
Pheast Therapeutics
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NCT06538337
Recruiting

Hypofractionated External Beam Radiotherapy With Adaptive Planning for Endometrial and Cervical Cancers

Enrollment
60 pts
Country
🇺🇸 United States
Jonsson Comprehensive Cancer Center
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NCT05579366 Phase 1, Phase 2
Recruiting

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

Enrollment
884 pts
Country
🇺🇸 United States
Genmab
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NCT05819892 Phase 1
Recruiting

Phase I Trial Testing the Safety and Tolerability of Chemoradiation Followed by Chemotherapy + Dostarlimab for Stage IIIC, Node Positive, Endometrial Cancer

Enrollment
21 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
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NCT07643012
Recruiting

Adaptive Daily MR-Guided Adjuvant Pelvic Therapy-Endometrial Cancer

Enrollment
30 pts
Country
🇺🇸 United States
Rutgers, The State University of Ne...
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NCT07524322 Phase 1
Recruiting

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

Enrollment
63 pts
Country
🇺🇸 United States
Regor Pharmaceuticals Inc.
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NCT05797831 Phase 2, Phase 3
Recruiting

Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer

Enrollment
268 pts
Country
🇺🇸 United States
Kartos Therapeutics, Inc.
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NCT06695845 Phase 2
Recruiting

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

Enrollment
200 pts
Country
🇺🇸 United States
Jazz Pharmaceuticals
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Frequently Asked Questions

How many endometrial cancer clinical trials are active in United States?
There are currently 22 active clinical trials for endometrial cancer with sites in United States, of which 22 are actively recruiting patients.
How can I join a endometrial cancer clinical trial in United States?
To join a endometrial cancer clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are endometrial cancer trials in United States?
Active endometrial cancer trials in United States span Phase 2, Phase 1, Phase 1, Phase 2, EARLY_Phase 1, Phase 3, Phase 2, Phase 3. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
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All United States Trials → Global endometrial cancer Trials → All Countries → All Trials →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology