🇺🇸 United States Country × Condition
colorectal cancer Clinical Trials in United States
Active clinical trials for colorectal cancer with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.
Active Trials: 29 // Recruiting: 29 Phases: Phase 1, Phase 1, Phase 2 // Updated: Daily
Total Trials
29
Recruiting Now
29
Country
🇺🇸 United States
Active Trials in United States (29)
NCT05787587 Phase 1
Recruiting
A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors
Enrollment
216 pts
Country
🇺🇸 United States
IDEAYA Biosciences
View Trial → NCT06349590 Phase 1, Phase 2
Recruiting
Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery
Enrollment
80 pts
Country
🇺🇸 United States
University of Chicago
View Trial → NCT03965234 Phase 1, Phase 2
Recruiting
Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases
Enrollment
99 pts
Country
🇺🇸 United States
Roswell Park Cancer Institute
View Trial → NCT05195970
Recruiting
Walnuts and Colon Health
Enrollment
200 pts
Country
🇺🇸 United States
UConn Health
View Trial → NCT06047379 Phase 1, Phase 2
Recruiting
Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
Enrollment
134 pts
Country
🇺🇸 United States
Neonc Technologies, Inc.
View Trial → NCT06973161
Recruiting
ESPERANZA: External Control Arm Study for T-DXd for Patients With HER2 IHC3+ Solid Tumors
Enrollment
105 pts
Country
🇺🇸 United States
AstraZeneca
View Trial → NCT06395519 Phase 1, Phase 2
Recruiting
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
Enrollment
120 pts
Country
🇺🇸 United States
858 Therapeutics, Inc.
View Trial → NCT07216105 Phase 1
Recruiting
FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors
Enrollment
113 pts
Country
🇺🇸 United States
Fate Therapeutics
View Trial → NCT05343013 Phase 2
Recruiting
TAS-102 With or Without Celecoxib in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy
Enrollment
25 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
View Trial → NCT06440005 Phase 1
Recruiting
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
Enrollment
80 pts
Country
🇺🇸 United States
Angiex, Inc.
View Trial → NCT07136077 Phase 2
Recruiting
A Phase 2 Trial of Fruquintinib and Tislelizumab in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy
Enrollment
20 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
View Trial → NCT07327489
Recruiting
Predicting Response to Immunotherapy From Analysis of Live Tumor Biopsies
Enrollment
2,000 pts
Country
🇺🇸 United States
Elephas
View Trial → NCT06580002 Phase 2
Recruiting
Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
Enrollment
51 pts
Country
🇺🇸 United States
University of California, Irvine
View Trial → NCT07227636 Phase 2
Recruiting
A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy
Enrollment
284 pts
Country
🇺🇸 United States
Memorial Sloan Kettering Cancer Cen...
View Trial → NCT05517811
Recruiting
Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection
Enrollment
400 pts
Country
🇺🇸 United States
University of Colorado, Denver
View Trial → NCT04282044 Phase 1
Recruiting
Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies
Enrollment
60 pts
Country
🇺🇸 United States
BioEclipse Therapeutics
View Trial → NCT05319314 Phase 1
Recruiting
GCC19CART for Patients With Metastatic Colorectal Cancer
Enrollment
30 pts
Country
🇺🇸 United States
Lyell Immunopharma, Inc.
View Trial → NCT05286814 Phase 2
Recruiting
PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma
Enrollment
70 pts
Country
🇺🇸 United States
National Cancer Institute (NCI)
View Trial → NCT04429542 Phase 1
Recruiting
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
Enrollment
292 pts
Country
🇺🇸 United States
Bicara Therapeutics
View Trial → NCT02328677
Recruiting
ColoCare Study - Colorectal Cancer Cohort
Enrollment
5,000 pts
Country
🇺🇸 United States
University of Utah
View Trial → NCT06342401
Recruiting
Early Onset Colorectal Cancer Detection
Enrollment
400 pts
Country
🇺🇸 United States
City of Hope Medical Center
View Trial → NCT06586515 Phase 1
Recruiting
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
Enrollment
630 pts
Country
🇺🇸 United States
Eli Lilly and Company
View Trial → NCT04585750 Phase 1, Phase 2
Recruiting
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Enrollment
300 pts
Country
🇺🇸 United States
PMV Pharmaceuticals, Inc
View Trial → NCT07310446
Recruiting
Collection of Samples From the United States Population for Optimization and Evaluation of Colorectal Cancer (CRC) Plasma Circulating Free-DNA (cfDNA) Marker Panel Performance
Enrollment
6,500 pts
Country
🇺🇸 United States
Universal Diagnostics
View Trial → NCT05576896 Phase 2
Recruiting
Hydroxychloroquine in Combination With Encorafenib and Cetuximab or Panitumumab in the Treatment of Metastatic BRAF-mutated Colorectal Cancer Refractory
Enrollment
43 pts
Country
🇺🇸 United States
Northwestern University
View Trial → NCT06445062 Phase 1, Phase 2
Recruiting
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
Enrollment
1,130 pts
Country
🇺🇸 United States
Revolution Medicines, Inc.
View Trial → NCT06281678 Phase 2
Recruiting
A Study of IBI363 in Subjects with Advanced Solid Malignancies
Enrollment
178 pts
Country
🇺🇸 United States
Innovent Biologics (Suzhou) Co. Ltd...
View Trial → NCT07321106 Phase 1
Recruiting
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer
Enrollment
80 pts
Country
🇺🇸 United States
Cartography Biosciences
View Trial → NCT07042243
Recruiting
The Florida ASCENT Study
Enrollment
100 pts
Country
🇺🇸 United States
University of Florida
View Trial → Frequently Asked Questions
How many colorectal cancer clinical trials are active in United States?
There are currently 29 active clinical trials for colorectal cancer with sites in United States, of which 29 are actively recruiting patients.
How can I join a colorectal cancer clinical trial in United States?
To join a colorectal cancer clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are colorectal cancer trials in United States?
Active colorectal cancer trials in United States span Phase 1, Phase 1, Phase 2, Phase 2. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.