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unresectable hepatocellular carcinoma

Total Trials
5
Recruiting Now
5
Trial Phases
Phase 1, Phase 2

ClinicalMetric tracks all active clinical trials for unresectable hepatocellular carcinoma sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — unresectable hepatocellular carcinoma Clinical Trials

How many clinical trials are currently recruiting for unresectable hepatocellular carcinoma?
ClinicalMetric currently tracks 5 actively recruiting clinical trials for unresectable hepatocellular carcinoma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 5. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for unresectable hepatocellular carcinoma?
unresectable hepatocellular carcinoma research spans Phase 1 (2 trials), Phase 2 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a unresectable hepatocellular carcinoma clinical trial?
Eligibility criteria for unresectable hepatocellular carcinoma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
2
Phase 2
2
Top Sponsors
Guilin Medical University, China 1 trial
Zhongda Hospital 1 trial
Zhiyong Huang 1 trial
Yoon Jun Kim 1 trial
Mayo Clinic 1 trial

Recruiting Clinical Trials

NCT07141056
Recruiting

The Impact of Emotional Stress on Immunotherapy Outcomes in Liver Cancer Patients: A Multi-Cohort Study

Enrollment
700 pts
Location
China
Sponsor
Guilin Medical University, Chi...
View Trial →
NCT06909708
Recruiting

SIRT Versus cTACE for Unresectable HCC (CHANCE2506)

Enrollment
108 pts
Location
China
Sponsor
Zhongda Hospital
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NCT06280313
Recruiting

Impact of Splenectomy on the Efficacy of Targeted Therapy and Immunotherapy in Unresectable HCC Patients With Cirrhotic Portal Hypertension

Enrollment
60 pts
Location
China
Sponsor
Zhiyong Huang
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NCT06911255 Phase 1, Phase 2
Recruiting

Safety and Efficacy of Tremelimumab+Durvalumab(MEDI4736)+TACE in Unresectable Hepatocellular Carcinoma

Enrollment
24 pts
Location
South Korea
Sponsor
Yoon Jun Kim
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NCT03942328 Phase 1, Phase 2
Recruiting

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

Enrollment
85 pts
Location
United States
Sponsor
Mayo Clinic
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology