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thyroid cancer

Total Trials
16
Recruiting Now
16
Trial Phases
Phase 2, Phase 1, Phase 3

Cancer clinical trials represent the largest single category of recruiting studies worldwide, encompassing everything from early-phase safety studies of novel oncology drugs to large Phase 3 comparisons against current standard-of-care chemotherapy regimens. The field has accelerated dramatically with the rise of immunotherapy, targeted therapies, and CAR-T cell treatments that have transformed outcomes for previously untreatable malignancies.

Trials include checkpoint inhibitors (PD-1/PD-L1 agents), KRAS inhibitors, ADC (antibody-drug conjugates), combination chemotherapy regimens, radiation protocols, and surgical technique comparisons. Many trials stratify by biomarker status (PD-L1 expression, TMB, MSI-H) to identify patients most likely to benefit.

The NCI, pharmaceutical sponsors, and academic cancer centers collectively fund thousands of oncology trials annually across every cancer type.

Frequently Asked Questions — thyroid cancer Clinical Trials

How many clinical trials are currently recruiting for thyroid cancer?
ClinicalMetric currently tracks 16 actively recruiting clinical trials for thyroid cancer, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 16. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for thyroid cancer?
thyroid cancer research spans Phase 1 (4 trials), Phase 2 (1 trial), Phase 3 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a thyroid cancer clinical trial?
Eligibility criteria for thyroid cancer trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
4
Phase 2
1
Phase 3
2
Top Sponsors
Fujian Medical University 2 trials
M.D. Anderson Cancer Center 1 trial
Istituto Auxologico Italiano 1 trial
National University Hospital, Singapore 1 trial
Adela, Inc 1 trial

Recruiting Clinical Trials

NCT06507878
Recruiting

Global Real World Data in Patients With Advanced Thyroid Cancer on Standard of Care and Specialized Interventions- Registry of Oncologic Outcomes With Testing and Treatment.

Enrollment
459 pts
Location
United States
Sponsor
M.D. Anderson Cancer Center
View Trial →
NCT05752604
Recruiting

Impact of Conventional Treatments and Clinical Variables on Thyroid Cancer

Enrollment
3,000 pts
Location
Italy
Sponsor
Istituto Auxologico Italiano
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NCT06923826 Phase 2
Recruiting

Sacituzumab Govitecan in Metastatic Salivary Gland and Thyroid Cancers (SG-SGTC)

Enrollment
32 pts
Location
Singapore
Sponsor
National University Hospital, ...
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NCT05366881
Recruiting

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

Enrollment
7,000 pts
Location
United States
Sponsor
Adela, Inc
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NCT07438847 Phase 1
Recruiting

177Lu-CTR-FAPI for the Treatment of Thyroid Cancer

Enrollment
12 pts
Location
China
Sponsor
SHAOYAN LIU
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NCT05355701 Phase 1
Recruiting

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

Enrollment
267 pts
Location
United States, Canad...
Sponsor
Pfizer
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NCT07524777
Recruiting

Ganoderma Spores Modulate the Gut-Brain Axis

Enrollment
300 pts
Location
China
Sponsor
Ling Zhiqiang
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NCT07419932
Recruiting

Response to Neoadjuvant Treatment in Locally Advanced Thyroid Cancer

Enrollment
120 pts
Location
China
Sponsor
Fujian Medical University
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NCT06554652 Phase 3
Recruiting

Selective Neck Dissection Versus Modified Neck Dissection in PTC

Enrollment
250 pts
Location
China
Sponsor
Fudan University
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NCT05999630 Phase 3
Recruiting

Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid Cancer

Enrollment
100 pts
Location
United States
Sponsor
Vanderbilt University Medical ...
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NCT07370675
Recruiting

Active Surveillance for Bethesda IV Thyroid Nodules

Enrollment
165 pts
Location
Denmark
Sponsor
Christian Grønhøj Larsen
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NCT06149637
Recruiting

Lateral Cervical Node Dissection in Differentiated Thyroid Cancer.

Enrollment
62 pts
Location
Colombia
Sponsor
Centro de Excelencia en Enferm...
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NCT06902376 Phase 1
Recruiting

XL092 and Cemiplimab in BRAF WT Thyroid Cancer

Enrollment
12 pts
Location
United States
Sponsor
UNC Lineberger Comprehensive C...
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NCT06498674
Recruiting

Clinical Application of AI-assisted Ultrasound Technology in the Preoperative Evaluation of Thyroid Cancer

Enrollment
300 pts
Location
China
Sponsor
Fujian Medical University
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NCT06771219 Phase 1
Recruiting

SLV-154 Treatment of Metastatic Solid Tumors

Enrollment
70 pts
Location
United States
Sponsor
Solve Therapeutics
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NCT03765333
Recruiting

GETNE Registration of Thyroid Cancer

Enrollment
20 pts
Location
Spain
Sponsor
Grupo Espanol de Tumores Neuro...
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology