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t lymphoblastic lymphoma

Total Trials
2
Recruiting Now
2
Trial Phases
Phase 1, Phase 2, EARLY_Phase 1

Lymphoma trials span diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, Hodgkin lymphoma, mantle cell lymphoma, and T-cell lymphomas — each with distinct biology and treatment response. CAR-T cell therapy has established a new standard in relapsed/refractory DLBCL, and trials now aim to move this approach earlier in the treatment sequence.

Active trials evaluate bispecific antibodies (mosunetuzumab, epcoritamab, glofitamab), next-generation CAR-T cell products (CD19/CD22 dual targets, BCMA-targeting), BTK inhibitors in B-cell lymphomas, and total metabolic volume on PET as a predictive biomarker for treatment adaptation.

Trial Phases
Phase 1
2
Phase 2
1
Top Sponsors
SWOG Cancer Research Network 1 trial
Zhejiang University 1 trial
NCT04315324 Phase 1, Phase 2
Recruiting

Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL)

Enrollment
67 pts
Location
United States
Sponsor
SWOG Cancer Research Network
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NCT06633341 EARLY_Phase 1
Recruiting

Targeting CD5 CAR-T Cells in the Treatment of r/r CD5+ T-lymphoma

Enrollment
30 pts
Location
China
Sponsor
Zhejiang University
View Trial →
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