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stage iii lung cancer ajcc v8

Total Trials
6
Recruiting Now
6
Trial Phases
Phase 4

Cancer clinical trials represent the largest single category of recruiting studies worldwide, encompassing everything from early-phase safety studies of novel oncology drugs to large Phase 3 comparisons against current standard-of-care chemotherapy regimens. The field has accelerated dramatically with the rise of immunotherapy, targeted therapies, and CAR-T cell treatments that have transformed outcomes for previously untreatable malignancies.

Trials include checkpoint inhibitors (PD-1/PD-L1 agents), KRAS inhibitors, ADC (antibody-drug conjugates), combination chemotherapy regimens, radiation protocols, and surgical technique comparisons. Many trials stratify by biomarker status (PD-L1 expression, TMB, MSI-H) to identify patients most likely to benefit.

The NCI, pharmaceutical sponsors, and academic cancer centers collectively fund thousands of oncology trials annually across every cancer type.

Frequently Asked Questions — stage iii lung cancer ajcc v8 Clinical Trials

How many clinical trials are currently recruiting for stage iii lung cancer ajcc v8?
ClinicalMetric currently tracks 6 actively recruiting clinical trials for stage iii lung cancer ajcc v8, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 6. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for stage iii lung cancer ajcc v8?
stage iii lung cancer ajcc v8 research spans Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a stage iii lung cancer ajcc v8 clinical trial?
Eligibility criteria for stage iii lung cancer ajcc v8 trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 4
1
Top Sponsors
Rutgers, The State University of New Jersey 1 trial
OHSU Knight Cancer Institute 1 trial
Thomas Jefferson University 1 trial
Roswell Park Cancer Institute 1 trial
Mayo Clinic 1 trial

Recruiting Clinical Trials

NCT04751747
Recruiting

Adaptive Radiation Planning for the Reduction of Radiation-Induced Toxicity in Patients With Stage II-IV Non-small Cell Lung Cancer

Enrollment
34 pts
Location
United States
Sponsor
Rutgers, The State University ...
View Trial →
NCT07405086 Phase 4
Recruiting

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

Enrollment
160 pts
Location
United States
Sponsor
OHSU Knight Cancer Institute
View Trial →
NCT05502523
Recruiting

The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer

Enrollment
100 pts
Location
United States
Sponsor
Thomas Jefferson University
View Trial →
NCT06869447
Recruiting

New York Better Breathing Study

Enrollment
100 pts
Location
United States
Sponsor
Roswell Park Cancer Institute
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NCT06075524
Recruiting

Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types

Enrollment
500 pts
Location
United States
Sponsor
Mayo Clinic
View Trial →
NCT06139627
Recruiting

Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy

Enrollment
180 pts
Location
United States
Sponsor
City of Hope Medical Center
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology