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soft tissue sarcoma

Total Trials
17
Recruiting Now
17
Trial Phases
Phase 2, Phase 1, Phase 1, Phase 2

ClinicalMetric tracks all active clinical trials for soft tissue sarcoma sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — soft tissue sarcoma Clinical Trials

How many clinical trials are currently recruiting for soft tissue sarcoma?
ClinicalMetric currently tracks 17 actively recruiting clinical trials for soft tissue sarcoma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 17. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for soft tissue sarcoma?
soft tissue sarcoma research spans Phase 1 (3 trials), Phase 2 (8 trials), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a soft tissue sarcoma clinical trial?
Eligibility criteria for soft tissue sarcoma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
3
Phase 2
8
Phase 4
1
Top Sponsors
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 1 trial
Beijing Tongren Hospital 1 trial
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 1 trial
Memorial Sloan Kettering Cancer Center 1 trial
QBiotics Group Limited 1 trial

Recruiting Clinical Trials

NCT04166006 Phase 2
Recruiting
A Phase II Study on Adjuvant Vaccination with Dendritic Cells Loaded with Autologous Tumor Homogenate in Resected Stage IV Rare Cancers.
Enrollment
51 pts
Location
Italy
Sponsor
Istituto Romagnolo per lo Stud...
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NCT07888114 Phase 1
Recruiting
Preliminary Clinical Study of Entinostat in Children With Malignant Soft Tissue Sarcoma Harboring PAX-family Gene Abnormalities
Enrollment
16 pts
Location
China
Sponsor
Beijing Tongren Hospital
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NCT05917301
Recruiting
Pre-operative Hypofractionated Proton Therapy
Enrollment
40 pts
Location
United States
Sponsor
Sidney Kimmel Comprehensive Ca...
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NCT06129903
Recruiting
Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma
Enrollment
60 pts
Location
United States
Sponsor
Memorial Sloan Kettering Cance...
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NCT05755113 Phase 2
Recruiting
A Clinical Study to Investigate the Efficacy of Intratumoral Tigilanol Tiglate in Soft Tissue Sarcoma
Enrollment
40 pts
Location
United States
Sponsor
QBiotics Group Limited
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NCT07920835 Phase 2
Recruiting
A Multicenter Phase II Clinical Trial Evaluating 68Ga-HX01 Injection for PET/CT Imaging
Enrollment
60 pts
Location
China
Sponsor
Hexin (Suzhou) Pharmaceutical ...
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NCT05000294 Phase 1, Phase 2
Recruiting
Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
Enrollment
29 pts
Location
United States
Sponsor
University of Florida
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NCT04181970
Recruiting
Observational Study, for Quality Assessment, of Sarcoma in European and Latin American Multidisciplinary NETWORK
Enrollment
5,000 pts
Location
Argentina, Brazil, C...
Sponsor
Grupo Espanol de Investigacion...
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NCT03175718
Recruiting
INPWT on Wound Complications & Clinical Outcomes After Lower Extremity Sarcoma Surgery Preop Radiation Therapy Patients
Enrollment
291 pts
Location
Canada
Sponsor
Dr. J. Werier
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NCT07917949 Phase 2
Recruiting
Zemetostat With Anlotinib in Patients With Recurrent/Metastatic Head and Neck Soft Tissue Sarcoma
Enrollment
34 pts
Location
China
Sponsor
Shanghai Ninth People's Hospit...
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NCT06506838 Phase 4
Recruiting
Anlotinib Combined With Doxorubicin and Radiotherapy as Neoadjuvant Treatment for Soft Tissue Sarcoma
Enrollment
39 pts
Location
China
Sponsor
Guangdong Provincial People's ...
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NCT06537596 Phase 1
Recruiting
89Zr-olaratumab Dosimetry in Participants With PDGFR Alpha Positive Solid Tumours and Soft Tissue Sarcoma
Enrollment
50 pts
Location
Australia
Sponsor
Telix Pharmaceuticals (Innovat...
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NCT06022159 Phase 2
Recruiting
A Study to Evaluate Pre-operative HYPOfractionated Radiation Therapy in Aged (≥ 70 Years Old) or "Fragile" (≥ 65 Years) Patients With Limb or Trunk Soft Tissue SARComa.
Enrollment
48 pts
Location
France
Sponsor
Institut Claudius Regaud
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NCT05051059
Recruiting
Assessment of the Functional Outcome and Quality of Life in Sarcoma Patients
Enrollment
60 pts
Location
Belgium
Sponsor
Universitaire Ziekenhuizen KU ...
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NCT06514313 Phase 2
Recruiting
Clinical Trial of VIM With VIT in Children With Relapsed and Refractory Soft Tissue Sarcoma.
Enrollment
110 pts
Location
China
Sponsor
Yizhuo Zhang
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NCT04589741 Phase 2
Recruiting
Toripalimab Combined With CAV/IE Regimen
Enrollment
134 pts
Location
China
Sponsor
Sun Yat-sen University
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NCT05761054
Recruiting
Sarcoma Preoperative Radiation With Simultaneous INTegrated Boost (SPRINT)
Enrollment
33 pts
Location
Italy
Sponsor
Azienda Ospedaliero-Universita...
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology