Medical Condition

soft tissue sarcoma

Total Trials

12

Recruiting Now

12

Trial Phases

Phase 2, Phase 3, Phase 1, Phase 2

ClinicalMetric tracks all active clinical trials for soft tissue sarcoma sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — soft tissue sarcoma Clinical Trials

How many clinical trials are currently recruiting for soft tissue sarcoma?

ClinicalMetric currently tracks 12 actively recruiting clinical trials for soft tissue sarcoma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 12. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for soft tissue sarcoma?

soft tissue sarcoma research spans Phase 1 (4 trials), Phase 2 (6 trials), Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a soft tissue sarcoma clinical trial?

Eligibility criteria for soft tissue sarcoma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

Phase 2

Phase 3

Top Sponsors

Institut Claudius Regaud 2 trials

Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 1 trial

Universität Münster 1 trial

Memorial Sloan Kettering Cancer Center 1 trial

Second Affiliated Hospital, School of Medicine, Zhejiang University 1 trial

Recruiting Clinical Trials

NCT04166006 Phase 2

Recruiting

A Phase II Study on Adjuvant Vaccination with Dendritic Cells Loaded with Autologous Tumor Homogenate in Resected Stage IV Rare Cancers.

Istituto Romagnolo per lo Stud...

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NCT05597917 Phase 3

Recruiting

tTF-NGR Randomized Study - STS

A Study to Evaluate Pre-operative HYPOfractionated Radiation Therapy in Aged (≥ 70 Years Old) or "Fragile" (≥ 65 Years) Patients With Limb or Trunk Soft Tissue SARComa.

Institut Claudius Regaud

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NCT03967834

Recruiting

Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma Group

Institut Claudius Regaud

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NCT04577014 Phase 1, Phase 2

Recruiting

Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma

Memorial Sloan Kettering Cance...

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NCT07243626 Phase 2

Recruiting

Efficacy and Safety of Envafolimab Plus Doxorubicin and Ifosfamide for Advanced Soft Tissue Sarcoma

Second Affiliated Hospital, Sc...

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NCT05109494 Phase 2

Recruiting

Hypofractionated vs Conventional Fractionated RT in Soft Tissue Sarcomas

University of Wisconsin, Madis...

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NCT04897321 Phase 1

Recruiting

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research H...

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NCT06500065

Recruiting

68Ga-DOTATATE PET/CT for the Diagnosis of Soft Tissue Sarcomas

Ohio State University Comprehe...

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NCT05621668 Phase 1

Recruiting

A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone Sarcoma

M.D. Anderson Cancer Center

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NCT07064018 Phase 1, Phase 2

Recruiting

Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

University of California, Irvi...

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NCT04921917

Recruiting

Exercise and Soft Tissue Sarcoma

Related Conditions

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology