← Browse by Condition
Medical Condition

severe aplastic anemia

Total Trials
7
Recruiting Now
7
Trial Phases
Phase 1, Phase 2, Phase 2

ClinicalMetric tracks all active clinical trials for severe aplastic anemia sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — severe aplastic anemia Clinical Trials

How many clinical trials are currently recruiting for severe aplastic anemia?
ClinicalMetric currently tracks 7 actively recruiting clinical trials for severe aplastic anemia, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 7. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for severe aplastic anemia?
severe aplastic anemia research spans Phase 1 (1 trial), Phase 2 (5 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a severe aplastic anemia clinical trial?
Eligibility criteria for severe aplastic anemia trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
1
Phase 2
5
Top Sponsors
National Heart, Lung, and Blood Institute (NHLBI) 2 trials
Hematology department of the 920th hospital 1 trial
Medical College of Wisconsin 1 trial
Peking University People's Hospital 1 trial
Institute of Hematology & Blood Diseases Hospital, China 1 trial

Recruiting Clinical Trials

NCT03173937 Phase 1, Phase 2
Recruiting
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome
Enrollment
37 pts
Location
United States
Sponsor
National Heart, Lung, and Bloo...
View Trial →
NCT06378060 Phase 2
Recruiting
Clinical Study on Modified Allogeneic Hematopoietic Stem Cell Transplantation Regimen for Severe Aplastic Anemia
Enrollment
30 pts
Location
China
Sponsor
Hematology department of the 9...
View Trial →
NCT05012111
Recruiting
Natural History of Acquired and Inherited Bone Marrow Failure Syndromes
Enrollment
1,000 pts
Location
United States
Sponsor
National Heart, Lung, and Bloo...
View Trial →
NCT06517641 Phase 2
Recruiting
Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia
Enrollment
60 pts
Location
United States
Sponsor
Medical College of Wisconsin
View Trial →
NCT07586735
Recruiting
A Novel Conditioning Regimen for Haplo-HSCT in Older Patients With SAA
Enrollment
64 pts
Location
China
Sponsor
Peking University People's Hos...
View Trial →
NCT06254560 Phase 2
Recruiting
Rituximab for Serious Aplastic Anemia With Platelet Transfusion Refractoriness
Enrollment
20 pts
Location
China
Sponsor
Institute of Hematology & Bloo...
View Trial →
NCT04099966 Phase 2
Recruiting
AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion
Enrollment
20 pts
Location
United States
Sponsor
Mitchell Cairo
View Trial →

Related Conditions

hypo plastic mds (1) myelodysplastic syndrome mds (1) telomere biology disorders (1) inherited bone marrow failure syndromes (1) aplastic anaemia (1) hematopoietic cell transplant (1) platelet transfusion refractoriness (1) acute leukemia (1) non hodgkin lymphoma (1) hodgkin lymphoma (1) kostmann (1) diamond blackfan anemia (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology