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residual limb pain

Total Trials
2
Recruiting Now
2
Trial Phases
Various

Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.

Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.

Frequently Asked Questions — residual limb pain Clinical Trials

How many clinical trials are currently recruiting for residual limb pain?
ClinicalMetric currently tracks 2 actively recruiting clinical trials for residual limb pain, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 2. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for residual limb pain?
residual limb pain research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a residual limb pain clinical trial?
Eligibility criteria for residual limb pain trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
Saglik Bilimleri Universitesi 1 trial
Prometei Pain Rehabilitation Center 1 trial

Recruiting Clinical Trials

NCT07420192
Recruiting
Evaluation of RPNI for Symptomatic Neuromas in Lower Limb Amputees
Enrollment
20 pts
Location
Turkey (Türkiye)
Sponsor
Saglik Bilimleri Universitesi
View Trial →
NCT05009394
Recruiting
Surgical Treatments for Postamputation Pain
Enrollment
110 pts
Location
United States, Austr...
Sponsor
Prometei Pain Rehabilitation C...
View Trial →

Related Conditions

symptomatic neuroma (1) phantom limb pain after amputation (1) neuropathic pain (1) lower extremity amputations (1) amputation neuroma (1) phantom limb pain (1) pain neuropathic (1) pain nerve (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology