Medical Condition

rectal adenocarcinoma

Total Trials

8

Recruiting Now

8

Trial Phases

Phase 1, Phase 2

ClinicalMetric tracks all active clinical trials for rectal adenocarcinoma sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — rectal adenocarcinoma Clinical Trials

How many clinical trials are currently recruiting for rectal adenocarcinoma?

ClinicalMetric currently tracks 8 actively recruiting clinical trials for rectal adenocarcinoma, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 8. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for rectal adenocarcinoma?

rectal adenocarcinoma research spans Phase 1 (1 trial), Phase 2 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a rectal adenocarcinoma clinical trial?

Eligibility criteria for rectal adenocarcinoma trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

Phase 2

Top Sponsors

Royal Marsden NHS Foundation Trust 1 trial

M.D. Anderson Cancer Center 1 trial

Alliance for Clinical Trials in Oncology 1 trial

Jonsson Comprehensive Cancer Center 1 trial

University of Colorado, Denver 1 trial

Recruiting Clinical Trials

NCT06854679

Recruiting

Dose Escalated Radiotherapy for Rectal Cancers Using MR-guided Radiotherapy

Royal Marsden NHS Foundation T...

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NCT02107105

Recruiting

Evaluation of Quality of Life and Utilities Following Surgical Treatment of Stage I-IV Rectal Cancer

M.D. Anderson Cancer Center

View Trial →

NCT07143487

Recruiting

Family Communications After Genetic Testing

Alliance for Clinical Trials i...

View Trial →

NCT04703101 Phase 1

Recruiting

Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer

Jonsson Comprehensive Cancer C...

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NCT07292298 Phase 2

Recruiting

Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

University of Colorado, Denver

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NCT06780787 Phase 2

Recruiting

FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

City of Hope Medical Center

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NCT07339904

Recruiting

ProLARS Trial: Prospective Longitudinal Follow-up of Low Anterior Resection Syndrome (LARS) and COREFO Score After Rectum Surgery in Patients Undergoing Upfront Surgery or Different Neo-adjuvant Treatment Regimens

University Hospital, Antwerp

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NCT06050447

Recruiting

Factors Affecting the Results of Treatment of Patients With Colorectal Cancer

Immanuel Kant Baltic Federal U...

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Related Conditions

stage iii rectal cancer ajcc v8 (4) stage ii rectal cancer ajcc v8 (3) stage iia rectal cancer ajcc v8 (3) stage i rectal cancer ajcc v8 (2) stage iib rectal cancer ajcc v8 (2) stage iic rectal cancer ajcc v8 (2) stage iiia rectal cancer ajcc v8 (2) stage iiib rectal cancer ajcc v8 (2) stage iiic rectal cancer ajcc v8 (2) stage iv rectal cancer ajcc v8 (2) colorectal adenocarcinoma (2) rectal cancer (2)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology