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proton therapy

Total Trials
5
Recruiting Now
5
Trial Phases
Phase 1, Phase 2, Phase 3

ClinicalMetric tracks all active clinical trials for proton therapy sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — proton therapy Clinical Trials

How many clinical trials are currently recruiting for proton therapy?
ClinicalMetric currently tracks 5 actively recruiting clinical trials for proton therapy, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 5. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for proton therapy?
proton therapy research spans Phase 1 (1 trial), Phase 2 (1 trial), Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a proton therapy clinical trial?
Eligibility criteria for proton therapy trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
1
Phase 2
1
Phase 3
1
Top Sponsors
Leiden University Medical Center 1 trial
Istituto Clinico Humanitas 1 trial
Institute of Hematology and Blood Transfusion, Czech Republic 1 trial
EBG MedAustron GmbH 1 trial
University of Aarhus 1 trial

Recruiting Clinical Trials

NCT04832620
Recruiting
Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas
Enrollment
40 pts
Location
Netherlands
Sponsor
Leiden University Medical Cent...
View Trial →
NCT07317245
Recruiting
HUmanitas PROtontherapy (HU-PRO)
Enrollment
500 pts
Location
Italy
Sponsor
Istituto Clinico Humanitas
View Trial →
NCT07532824 Phase 1, Phase 2
Recruiting
Proton-Based Total Marrow Irradiation for Allogeneic Transplantation in High-Risk AML/MDS
Enrollment
16 pts
Location
Czechia
Sponsor
Institute of Hematology and Bl...
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NCT04894643
Recruiting
Preoperative, Proton- Radiotherapy Combined With Chemotherapy for Borderline Resectable Pancreatic Cancer
Enrollment
10 pts
Location
Austria
Sponsor
EBG MedAustron GmbH
View Trial →
NCT05055648 Phase 3
Recruiting
PROton Versus Photon Therapy for Esophageal Cancer - a Trimodality Strategy
Enrollment
396 pts
Location
Belgium, Denmark, Fr...
Sponsor
University of Aarhus
View Trial →

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology